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pro vyhledávání: '"Dhanalakshmi Chinnasamy"'
Autor:
Jonathan Treisman, Nachimuthu Chinnasamy, Geoffrey P. Margison, James Neuenfeldt, John P. Hanson, Dhanalakshmi Chinnasamy, Leslie J. Fairbairn
Publikováno v:
Human Gene Therapy. 15:758-769
Lentiviral vectors are capable of efficiently transducing nondividing and slowly dividing cells, including hematopoietic stem cells, resulting in stable integration and sustained transgene expression. We constructed human immunodeficiency virus type
Autor:
Nachimuthu Chinnasamy, Dhanalakshmi Chinnasamy, John F. Toso, Patrick Hwu, Richard A. Morgan, Fabio Candotti, Réjean Lapointe
Publikováno v:
Human Gene Therapy. 11:1901-1909
Dendritic cells (DCs) are potent antigen-presenting cells and are capable of activating naive T cells. Gene transfer of tumor antigen and cytokine genes into DCs could be an important strategy for immunotherapeutic applications. Dendritic cells deriv