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Autor:
Eric M. Mortensen, Erin L. Mead, Cheryl Oncken, Maciej L. Goniewicz, Mario F. Perez, Nkiruka C. Atuegwu
Publikováno v:
J Womens Health (Larchmt)
Background: Electronic cigarettes (e-cigarettes) generally have a more favorable toxicant profile than conventional cigarettes; however, limited information exists for women of reproductive age (WRA). Our aim was to compare biomarkers of toxicant exp
Autor:
Karen Wong, Elaine M. Jagoda, Jurgen Seidel, Amy K. LeBlanc, Ling Ren, Michael V. Green, Jennifer L Matta, Peter L. Choyke, Elijah F. Edmondson, Shan Huang, Anita T. Ton, Tim Phelps, Jyoti Roy, Donna Butcher, Kwamena E. Baidoo, Stephen Adler
Publikováno v:
Cancer Biother Radiopharm
Background: Patients with osteoblastic bone metastases are candidates for radium-223 ((223)RaCl(2)) therapy and may undergo sodium fluoride-18 ((18)F-NaF) positron emission tomography-computed tomography imaging to identify bone lesions. (18)F-NaF ha
Publikováno v:
Journal of Women's Health. 27:1225-1232
To investigate the efficacy and safety of estradiol valerate (EV)/dienogest (DNG) for the management of heavy menstrual bleeding (HMB) in Asian and non-Asian women desiring contraception.In this multicenter, double-blind, phase III study, women were
Autor:
Jennifer M O'Connor, Andrea E. Wahner Hendrickson, Jason D. Doles, Olivia Huston, Kelly A. Hogan, Aminah Jatoi
Publikováno v:
Journal of Palliative Medicine. 21:1334-1338
Background: More than 80% of patients with advanced cancer develop weight loss. Because preclinical data suggest poly (ADP-ribose) polymerase (PARP) inhibitors can treat this weight loss, this study was undertaken to explore the PARP inhibitor velipa
Publikováno v:
Journal of Women's Health. 26:214-221
For nonvalvular atrial fibrillation (NVAF), novel oral anticoagulants (NOACs) have been found noninferior to warfarin for stroke/systemic embolization prevention, and major bleeding events. Recent meta-analysis of NOACs versus warfarin in atrial fibr
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 31:287-294
Purpose: Directly radioiodinated [131I]-rituximab has been developed as a radioimmunotherapeutic agent in patients with CD20-positive B cell non-Hodgkin's lymphoma. However, there are concerns over its in vivo catabolism and deiodination. A novel rad
Autor:
Paola Nasta, Giampiero Carosi, Massimo Puoti, Gabriella Verucchi, Ivana Maida, E. Angeli, Emanuele Pontali, Claudio Iannacone, Anna Maria Cattelan, Mariarosaria Giralda, Antonietta Caputo
Publikováno v:
Journal of Women's Health. 24:159-164
BACKGROUND: This was a post-hoc analysis of the Optimized Pegylated interferons Efficacy and anti-Retroviral Approach (OPERA) study, originally designed to document routine clinical and treatment data in HIV/HCV coinfected patients treated with pegyl
Autor:
Xiangyang Li, Xueru Fan, Yabin Duan, Junbo Zhu, Xue-Jun Wang, Yong-Ping Li, Xingchen Yao, Xiaodong Su
Publikováno v:
High Altitude Medicine & Biology. 15:491-496
The effects of exposure to acute and chronic high altitude hypoxia on the activity and expression of CYP2E1 and CYP3A1 were examined in rats. Rats were divided into low altitude (LA, 400 m), acute moderate altitude hypoxia (AMH, 2800 m), chronic mode
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 28:441-449
The studies described herein assess the potential of combining platinum-based chemotherapy with high-linear energy transfer (LET) α-particle-targeted radiation therapy using trastuzumab as the delivery vehicle. An initial study explored the combinat
Publikováno v:
DNA and Cell Biology. 32:228-235
Chromatin has been successfully used as a tool for the study of genome function in cancers. Vincristine as a vinca alkaloid anticancer drug exerts its action by binding to tubulins. In this study the effect of vincristine on DNA and chromatin was inv