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Autor:
Paul Fernyhough, Eftekhar Eftekharpour
Publikováno v:
Antioxidants & Redox Signaling. 37:578-596
Significance. This review highlights the many intracellular processes generating reactive oxygen species (ROS) in the peripheral nervous system in the context of type 1 diabetes. The major sources ...
Publikováno v:
Journal of Interferon & Cytokine Research. 42:1-7
Inflammatory bowel diseases (IBD) are chronic inflammatory gastrointestinal diseases characterized by dysregulation of the intestinal epithelial barrier (IEB) and intermittent relapses. Recent data show that the glial cell line-derived neurotrophic f
Autor:
Hyo In Kim, Elzbieta Kaczmarek, Ingred Riça, Jinbong Park, Barbora Konečná, Kiyoshi Itagaki, Carl J. Hauser
Publikováno v:
Antioxid Redox Signal
Significance: Sepsis is a major public health concern, with high mortality and morbidity, especially among patients undergoing trauma. It is characterized by a systemic inflammatory response syndrome (SIRS) occurring in response to infection. Althoug
Autor:
Judith Hellman, Jérémie Joffre
Publikováno v:
Antioxidants & Redox Signaling. 35:1291-1307
Significance: Under homeostatic conditions, the endothelium dynamically regulates vascular barrier function, coagulation pathways, leukocyte adhesion, and vasomotor tone. During sepsis and acute inflammation, endothelial cells (ECs) undergo multiple
Publikováno v:
Antioxid Redox Signal
Significance: Sepsis is defined as a life-threatening organ dysfunction caused by dysregulated host response to infection. This leads to an uncontrolled inflammatory response at the onset of infection, followed by immunosuppression. The development o
Publikováno v:
Journal of Interferon & Cytokine Research. 41:375-384
Inflammatory cytokines has been of great interest in the field of colorectal cancer (CRC) tumor immunology in recent years. As an anti-inflammatory interleukin (IL), IL-38 may contribute to the ear...
Publikováno v:
Journal of Interferon & Cytokine Research. 41:302-306
Psoriasis is a chronic disorder characterized by a complex interplay between keratinocytes and inflammatory mediators. In a previous study, we evaluated diacerein's ability to diminish interleukin (IL)-1's proinflammatory effects on cultured primary
Publikováno v:
DNA and Cell Biology. 40:858-868
In late December 2019, a new kind of Coronavirus called severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) was officially identified in Wuhan, China. In March 2020, SARS-CoV-2 was declared a pandemic by the World Health Organization (WHO),
Publikováno v:
Journal of Interferon & Cytokine Research. 41:220-233
Cervical cancer (CC) is a common malignancy in women. Long noncoding RNA LINC00899 plays a role in cancer, but its effects in CC are unknown. Our experiment aims to investigate the specific effects of LINC00899 in CC. LINC00899 was lowly expressed in
Publikováno v:
Journal of Interferon & Cytokine Research. 41:12-19
The elevation of circulating interleukin 6 (IL-6) is one of the major molecular characteristics of endometrial carcinoma. In this study, we investigated the role of coiled-coil domain-containing 68 (CCDC68) in IL-6-associated endometrial carcinoma pr