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Autor:
Melanie Boerries, Oliver Thomusch, Michael Rassner, Matthias Kroiss, Paul la Rosee, Juri Ruf, Konrad Aumann, Cornelius Miething, Christine Dierks, Patrick Metzger, Tilmann Schumacher, Nikolas von Bubnoff, Selina Kiefer, Katharina Laubner, Christian Weißenberger, Claudius Klein, Andreas Zielke, Harald Weiss, Constantin Smaxwil, Justus Duyster, Philipp T. Meyer, Jochen Seufert
Publikováno v:
Thyroid
Background: Anaplastic thyroid carcinoma (ATC) and metastatic poorly differentiated thyroid carcinomas (PDTCs) are rare aggressive malignancies with poor overall survival (OS) despite extensive multimodal therapy. These tumors are highly proliferativ
Publikováno v:
DNA and Cell Biology. 40:469-481
Bladder cancer (BC) is a common genitourinary malignancy worldwide. However, the molecular pathogenesis of BC remains unclear. The current study conducted bioinformatic analyses to discover key genes involved in BC progression. A total of 375 differe
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 35:563-569
Objective: To prevent postoperative relapse after HOLRBT, we compared postoperative adjuvant therapies. Methods: One hundred fifty patients with non-muscle invasive bladder cancer (NMIBC) were meanly divided into three groups: A, B, and C. Group A pa
Publikováno v:
Human Gene Therapy. 31:891-903
Oncolytic adenoviruses (OAds) are promising agents for cancer therapy, representing a novel therapeutic strategy for pancreatic ductal adenocarcinoma (PDAC). However, there are challenges associated with the successful use of an OAd alone, involving
Publikováno v:
Journal of Computational Biology. 27:1041-1054
The early diagnosis of lung squamous cell carcinoma (LUSC) is difficult, causing an unsatisfactory prognosis. Therefore, the 5-year survival rate of LUSC is poor. This study aimed at screening the potential diagnostic and prognostic markers for LUSC.
Publikováno v:
Thyroid
Background: Thyroid immune-related adverse events (IRAEs) have been reported more frequently with programmed cell death protein-1 (PD-1) inhibitors than cytotoxic T lymphocyte antigen 4 (CTLA-4) inhibitors, but there is limited data describing endocr
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 34:436-443
The Wnt/β-catenin signaling pathway is one of the highly conserved signaling pathway widely reported to play essential roles in the development of various tumors and human cancers, thus serving as a potential target for anticancer therapy. However,
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 34:355-361
Background: Kinesin Family Member 3B (KIF3B) is one of the most ubiquitously expressed KIFs, which is related to numerous physiological responses. KIF3B has also been implicated in carcino...
Autor:
Jonghwa Ahn, Dong Eun Song, Won Gu Kim, Min Ji Jeon, Young Kee Shong, Tae Yong Kim, Eyun Song, Hye-Seon Oh, Won Bae Kim
Publikováno v:
Thyroid. 29:824-829
Background: The lymphocyte-to-monocyte ratio (LMR), which reflects the tumor-infiltrating immune cell status and host immunity, has been reported as a prognostic marker in various cancers. The aim ...
Publikováno v:
DNA and Cell Biology. 38:541-548
The aim of this research was to verify the mutation rate of the ring finger protein 43 (RNF43) of the transmembrane E3 ubiquitin ligase and investigate the influence of single nucleotide polymorphisms (SNPs) rs2257205 in RNF43 in a Chinese colorectal