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of 26
pro vyhledávání: ''
Autor:
Melanie Boerries, Oliver Thomusch, Michael Rassner, Matthias Kroiss, Paul la Rosee, Juri Ruf, Konrad Aumann, Cornelius Miething, Christine Dierks, Patrick Metzger, Tilmann Schumacher, Nikolas von Bubnoff, Selina Kiefer, Katharina Laubner, Christian Weißenberger, Claudius Klein, Andreas Zielke, Harald Weiss, Constantin Smaxwil, Justus Duyster, Philipp T. Meyer, Jochen Seufert
Publikováno v:
Thyroid
Background: Anaplastic thyroid carcinoma (ATC) and metastatic poorly differentiated thyroid carcinomas (PDTCs) are rare aggressive malignancies with poor overall survival (OS) despite extensive multimodal therapy. These tumors are highly proliferativ
Autor:
Min Ji Jeon, Young Kee Shong, Meihua Jin, Jonghwa Ahn, Tae Yong Kim, Dong Eun Song, Sang-Yeob Kim, Yeon-Mi Ryu, Won Bae Kim, Eyun Song, Won Gu Kim
Publikováno v:
Thyroid. 31:61-67
Background: Advanced thyroid cancers, including differentiated thyroid carcinoma (DTC) with distant metastasis, and anaplastic thyroid carcinoma (ATC), are associated with poor clinical outcomes an...
Publikováno v:
Thyroid
Background: Thyroid immune-related adverse events (IRAEs) have been reported more frequently with programmed cell death protein-1 (PD-1) inhibitors than cytotoxic T lymphocyte antigen 4 (CTLA-4) inhibitors, but there is limited data describing endocr
Autor:
Lei Zhang, Bao Guan, Liqun Zhou, Qun He, Xuesong Li, Zhengqing Bao, Shiming He, Dong Fang, Gengyan Xiong, Xinyu Yang
Publikováno v:
Genetic Testing and Molecular Biomarkers. 23:797-806
Aims: The prognostic significance of murine double minute 2 (MDM2) expression remains unknown in patients with upper tract urothelial carcinoma (UTUC). This study was designed to evaluate MDM2 expr...
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 34:504-510
Objectives: The present study aimed to retrospectively compare the clinical and imaging characteristics and laboratory data of patients with malignant tumor concurrent with acute ischemic ...
Autor:
Qinghai Ji, Yu-Long Wang, Cui-Wei Li, Wen-Jun Wei, Ben Ma, Rong-Liang Shi, Peng-Cheng Yu, Li-Cheng Tan, Bo-Wen Lei, Jia-Qian Hu, Yu Wang, Nai-Si Huang, Yan Zhang, Weibo Xu, Xiao Shi, Tong-Zhen Chen, Xiao Wang, Jie Wang
Publikováno v:
Thyroid. 29:1269-1278
Background: Expression of the programmed death-ligand 1 (PD-L1) in medullary thyroid carcinoma (MTC) has been rarely reported. In this study, we evaluated PD-L1 positivity in MTC and analyzed its c...
Autor:
Leila Shobab, Cristiane Gomes-Lima, Leonard Wartofsky, Kenneth D. Burman, Alexander Zeymo, Rebecca Feldman, Jacqueline Jonklaas
Publikováno v:
Thyroid. 29:1262-1268
Background: Six to 20% of thyroid cancer (TC) patients develop distant metastases, and one-third become radioiodine refractory (RAIR). Available targeted therapies increase progression-free surviva...
Autor:
Jonghwa Ahn, Dong Eun Song, Won Gu Kim, Min Ji Jeon, Young Kee Shong, Tae Yong Kim, Eyun Song, Hye-Seon Oh, Won Bae Kim
Publikováno v:
Thyroid. 29:824-829
Background: The lymphocyte-to-monocyte ratio (LMR), which reflects the tumor-infiltrating immune cell status and host immunity, has been reported as a prognostic marker in various cancers. The aim ...
Publikováno v:
DNA and Cell Biology. 38:541-548
The aim of this research was to verify the mutation rate of the ring finger protein 43 (RNF43) of the transmembrane E3 ubiquitin ligase and investigate the influence of single nucleotide polymorphisms (SNPs) rs2257205 in RNF43 in a Chinese colorectal
Low Gene Dosage ofCdc42Is Not Associated with Protein Dysfunction in Patients with Colorectal Cancer
Autor:
Adam Aguirre, Ximena Calderón, Claudia Hoepfner, Jaime Meléndez, Andrés Azócar, Karin Alvarez, Matías González-Quiroz, Ingrid Oyarzun, Francisco López-Köstner, Rodrigo Quera
Publikováno v:
DNA and Cell Biology. 35:819-827
High incidence of Rho Cdc42-GTPase overexpression has been found in Colorectal Cancer (CRC) samples, suggesting its potential role in tumor development. However, no conclusive studies have shown the lack of mutations and/or copy number of Cdc42 gene