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Autor:
Hicham El Bouhaddoutti, Rui Manuel Reis, Nada Lahmidani, S. Bennis, Jean Paul Nshizirungu, Karim Ibn Majdoub, Marta Viana-Pereira, Ihsane Mellouki, Sidi Adil Ibrahimi, Dafr-Allah Benajah, Sónia Pires Celeiro
Publikováno v:
Genetic Testing and Molecular Biomarkers. 25:116-123
Aim: To investigate correlations between microsatellite instability (MSI) and the phenotype, clinicopathological features, and overall survival (OS) in Moroccan gastric cancer (GC) patients. We eva...
Autor:
Min Ji Jeon, Young Kee Shong, Meihua Jin, Jonghwa Ahn, Tae Yong Kim, Dong Eun Song, Sang-Yeob Kim, Yeon-Mi Ryu, Won Bae Kim, Eyun Song, Won Gu Kim
Publikováno v:
Thyroid. 31:61-67
Background: Advanced thyroid cancers, including differentiated thyroid carcinoma (DTC) with distant metastasis, and anaplastic thyroid carcinoma (ATC), are associated with poor clinical outcomes an...
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 34:529-536
Background: MicroRNA-589-5p (miR-589-5p) has been recently reported to be aberrantly regulated in hepatocellular carcinoma, but its functional role and molecular mechanisms still remains u...
Autor:
Hyun Tae Shin, Young Lyun Oh, Sun Wook Kim, Joon Seol Bae, Seo Young Sohn, Chang-Seok Ki, Jae Hoon Chung, Woong-Yang Park
Publikováno v:
Thyroid. 26:672-682
Distant metastases uncommonly occur in differentiated thyroid carcinoma (DTC), but they are a frequent cause of thyroid cancer-related death. Genomic alterations in metastatic tumors, and the relationship with their corresponding primary tumors in DT
Autor:
Yi-Zhou Yao, Roderick J. Clifton-Bligh, Michael Mond, Peter J. Fuller, Christopher Gilfillan, Martyn Bullock
Publikováno v:
Thyroid. 25:904-910
Population-based studies have demonstrated an association of single nucleotide polymorphisms close to the thyroid transcription factor forkhead box E1 (FOXE1) gene with thyroid cancer. The dysregulation of forkhead proteins is increasingly recognized
Autor:
Kyu-Beom Kwack, Gwangil Kim, Ji-Ye Song, Chan Lee, Tae-Heon Kim, Haeyoun Kang, Ah-Young Kwon, Jin-Hyung Heo, Ju-Yeon Jeong, Hee Jung An
Publikováno v:
Stem Cells and Development. 24:1521-1535
Ovarian carcinoma is a highly lethal malignancy due to frequent relapse and drug resistance. Cancer stem cells (CSCs) are thought to contribute significantly to disease relapse and drug resistance. In this study, a subpopulation of CSCs of ovarian ca
The microRNA-367 Inhibits the Invasion and Metastasis of Gastric Cancer by Directly Repressing Rab23
Publikováno v:
Genetic Testing and Molecular Biomarkers. 19:69-74
Dysregulated expression of microRNAs is often found in gastric cancer, and it contributes to the pathogenesis of gastric cancer via regulation of the cell cycle, proliferation, apoptosis, migration, and invasion.In this study, we aimed to investigate
Autor:
Eric Casal Ide, Maria Rosa Pelizzo, Raffaele Pezzani, Loris Bertazza, Laura Zambonin, Mariangela Zane, Franco Mantero, Beatrice Rubin, Alessandro Bulfone, Andrea Cristiani, Susi Barollo, Stefano Moro, Gianmaria Pennelli, Carla Mucignat-Caretta, Caterina Mian, Marco Redaelli
Publikováno v:
Thyroid. 24:809-819
Papillary thyroid carcinoma (PTC) is the most common malignant tumor of the thyroid gland, accounting for 74-80% of all thyroid cancers. The 1799TA transversion is an activating mutation of the BRAF oncogene that is common in and specific to conventi
Autor:
Francine M. Quan, Walter D.Y. Quan
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 29:58-61
Outpatient daily intravenous infusions of interleukin-2 (IL-2) have been developed to maintain anticancer activity and decrease toxicity of this agent against kidney cancer. Lymphokine activated killer cell (LAK) numbers are increased with these IL-2
Autor:
Tülin Öztürk, Allison Pinar Eronat, Neslihan Saygili, Fatih Seyhan, Basak Akadam-Teker, Figen Aksoy, Oğuz Öztürk, Hulya Yilmaz-Aydogan, Aynur Daglar-Aday, Bahar Toptaş
Publikováno v:
DNA and Cell Biology. 32:13-18
The aim of this study was to investigate the association between the BRAF V600E mutation incidence and histopathologic prognostic risk factors for papillary thyroid carcinoma (PTC) on the Turkish population. The contribution of BRAF V600E mutation in