Zobrazeno 1 - 10
of 874
pro vyhledávání: '"CELL death"'
Publikováno v:
Autophagy. 17(1):1-382
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have als
Autor:
Simon Bressendorff, Daniel Hofius, Ohkmae K. Park, Morten Petersen, Eleazar Rodriguez, David Munch
Publikováno v:
Autophagy
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Munch, D, Rodriguez, E, Bressendorff, S, Park, O K, Hofius, D & Petersen, M 2014, ' Autophagy deficiency leads to accumulation of ubiquitinated proteins, ER stress, and cell death in Arabidopsis ', Autophagy, vol. 10, no. 9, pp. 1579-1587 . https://doi.org/10.4161/auto.29406
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Munch, D, Rodriguez, E, Bressendorff, S, Park, O K, Hofius, D & Petersen, M 2014, ' Autophagy deficiency leads to accumulation of ubiquitinated proteins, ER stress, and cell death in Arabidopsis ', Autophagy, vol. 10, no. 9, pp. 1579-1587 . https://doi.org/10.4161/auto.29406
Autophagy is a homeostatic degradation and recycling process that is also involved in defense against microbial pathogens and in certain forms of cellular suicide. Autophagy has been proposed to negatively regulate plant immunity-associated cell deat
Autor:
Yuan Shuo Hsueh, Li-Tzong Chen, Chueh Chuan Yen, Chien-Feng Li, Nai Jung Chiang, Neng Yao Shih
Publikováno v:
Autophagy
Gastrointestinal stromal tumor (GIST) is a prototype of mutant KIT oncogene-driven tumor. Prolonged tyrosine kinase inhibitor (TKI) treatment may result in a resistant phenotype through acquired secondary KIT mutation. Heat shock protein 90 (HSP90AA1
Autor:
Gregg B. Morin, Sharon M. Gorski, Lindsay DeVorkin, Ying-Chen Claire Hou, Courtney Choutka, Nancy Erro Go, Annie Moradian
Publikováno v:
Autophagy
The 2 main degradative pathways that contribute to proteostasis are the ubiquitin-proteasome system and autophagy but how they are molecularly coordinated is not well understood. Here, we demonstrate an essential role for an effector caspase in the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331f82eb3a22d51cc92fa57ec048f52a
https://resolver.caltech.edu/CaltechAUTHORS:20170822-072225587
https://resolver.caltech.edu/CaltechAUTHORS:20170822-072225587
Autor:
Xiaofang Sun, Daolin Tang
Publikováno v:
Autophagy
HMGB1 (high mobility group box 1) is a multifunctional, ubiquitous protein located inside and outside cells that plays a critical role in various physiological and pathological processes including cell development, differentiation, inflammation, immu
Autor:
Keisuke Tabata, Akiko Nozoe, Kanae Shirahama-Noda, Tamotsu Yoshimori, Takeshi Noda, Shintaro Kira
Publikováno v:
Autophagy
Autophagy is an intracellular degradation process that delivers cytosolic material to lysosomes and vacuoles. To investigate the mechanisms that regulate autophagy, we performed a genome-wide screen using a yeast deletion-mutant collection, and found
Autor:
Alessandra Romagnoli, Ellen Wirawan, Saskia Lippens, Peter Vandenabeele, Gian Maria Fimia, Tom Vanden Berghe, Mauro Piacentini
Publikováno v:
Autophagy; Vol 8
Beclin1(Atg6) is a well-known key regulator of autophagy. Although Beclin1 is enzymatically inert, it governs the autophagic process by regulating PtdIns3KC3-dependent generation of phosphatidylinositol3-phosphate (PtdIns(3)P) and the subsequent recr
Autor:
Elpida Tsika, Darren J Moore
Publikováno v:
Small GTPases
Mutations in the leucine-rich repeat kinase 2 (LRRK2, PARK8, OMIM 607060) gene represent the most common known cause of hereditary Parkinson's disease (PD) with late-onset and dominant inheritance. LRRK2 protein is composed of multiple domains includ