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Autor:
Seock-Ah Im, Jee Hyun Kim, Jin-Young Jang, Do-Youn Oh, Sae-Won Han, Yung-Jue Bang, Sung W. Ha, Sun Whe Kim, Jihyun Kwon, Eui Kyu Chie, Jae Sung Kim, Tae-You Kim, Kyung-Hun Lee
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose Despite curative resection, the 5-year survival for patients with resectable pancreatic cancer is less than 20%. Recurrence occurs both locally and at distant sites and effective multimodality adjuvant treatment is needed.Materials and Method
Autor:
Tae Min Kim, Jeong Mo Bae, Sung Hye Park, Jin Wook Kim, Joo Ho Lee, Hongseok Yun, Changhee Park, Chul-Kee Park, Soon-Tae Lee, Seung Hong Choi
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
PurposeThe treatment outcomes and genomic profiles of diffuse midline glioma (DMG) in adult patients are rarely characterized. We performed a retrospective study to evaluate the clinicogenomic profiles of adult patients with brain DMG.Materials and M
Autor:
Hyung Soon Park, Hee Yeon Lee, Hye Sung Won, Young Joon Yang, Jae Ho Byun, Ji Hyung Hong, Jieun Lee, In Sook Woo, Kabsoo Shin, Sang Hoon Chun, Ji Hyun Yang
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
PurposeUse of cyclin-dependent kinase 4/6 inhibitors improved survival outcome of hormone receptor (HR) positive metastatic breast cancer (MBC) patients, including Asian population. However, Asian real-world data of palbociclib is limited. We analyze
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose There are unmet needs associated with the current treatment strategies for relapsed/refractory diffuse large B-cell lymphoma (DLBCL) due to the poor treatment outcomes of these strategies. Roflumilast, a selective phosphodiesterase-4 inhibito
Autor:
Miso Kim, Changhee Park, Bhumsuk Keam, Dong Wan Kim, Tae Min Kim, Kyung Chul Moon, Se Hyun Kim, Yu Jung Kim, Yoonjin Kwak
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
PURPOSE Angiosarcoma is a highly aggressive mesenchymal tumor. Although systemic chemotherapy is often considered for the inoperable or metastatic angiosarcoma, the outcome of such treatment is unsatisfactory and poorly delineated. Materials and Meth
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose This study aimed to develop a nomogram for predicting pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (CRT) in patients with esophageal squamous cell carcinoma (ESCC) by integrating hematological biomarkers and clinicop
Autor:
Heung Tae Kim, Youngjoo Lee, Mihong Choi, Jin Soo Lee, Geon Kook Lee, Hye Jin Won, Jungnam Joo, Ji-Youn Han, Kun Young Lim, Soohyun Lee
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
PurposeSquamous cell carcinomas (SqCC) of the lung often express high levels of thymidylate synthase (TS), which is associated with primary resistance to pemetrexed. We explored the efficacy of pemetrexed in a selected population of patients with lun
Autor:
Jing Chen, Feihu Yan, Yang Yao, Zhiwei Li, Dan Wang, Bo-Jun Wang, Jie Lian, Jia-Ni Yang, Chunhui Zhang, Ruiyang Li, Lin Fang, Changjie Lou, Yibing Bai, Chao Liu, Shuling Han, Yanqiao Zhang
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose Systemic inflammatory response is a critical factor that promotes the initiation and metastasis of malignancies including pancreatic cancer (PC). This study was designed to determine and compare the prognostic value of neutrophil-to-lymphocyt
Autor:
Si-Qi Dong, Lian-Jing Cao, Tong-Min Wang, Pei-Fen Zhang, Wen-Qiong Xue, Jing-Wen Huang, Yong-Qiao He, Zi-Yi Wu, Xiao-Hui Zheng, Xi-Zhao Li, Wei Hua Jia, Da-Wei Yang, Jiang-Bo Zhang
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose Capecitabine is an extensively used oral prodrug of 5-fluorouracil in treatment of colon cancer and is known to cause hand-foot syndrome (HFS). As the target enzyme for capecitabine, thymidylate synthase (TYMS) plays a key role for 5-fluorour
Autor:
Shin Hwang, Hee-Sang Hwang, Seung-Mo Hong, Dae Wook Hwang, Do Hyun Park, Ki-Hun Kim, Baek-Yeol Ryoo, Kyu-Pyo Kim, Jae Ho Jeong, Tae Jun Song, Changhoon Yoo, Dongwook Oh, Junho Kang, Sang Soo Lee, Song Cheol Kim, Jin-Hong Park
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose The current standard chemotherapy for advanced biliary tract cancer (BTC) has limited benefit, and novel therapies need to be investigated. Materials and MethodsIn this prospective cohort study, programmed death ligand-1 (PD-L1)–positive BT