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pro vyhledávání: ''
Autor:
Hogeun Kim, Nam Kyu Kim, Yoon Jung Choi, Seung Hyuk Baik, Hye Sun Lee, Jeonghyun Kang, Im-kyung Kim, Kang Young Lee
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose The role of tumor-infiltrating lymphocytes (TILs) in predicting lymph node metastasis (LNM) in patients with T1 colorectal cancer (CRC) remains unclear. Furthermore, clinical utility of a machine learning–based approach has not been widely
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
PurposeMesenchymal epithelial transition (MET) is a proto-oncogene that encodes a heterodimeric transmembrane receptor tyrosine kinase for the hepatocyte growth factor. Aberrant MET signaling has been described in several solid tumors—especially no
Autor:
Yun Kyung Kang, Eun Sun Jung, Dong-Wook Kang, Haeryoung Kim, Kyoung Bun Lee, Soyeon An, Mee-Yon Cho, Youn Wha Kim, Sangjeong Ahn, Do Youn Park, Joon Mee Kim, Jo-Heon Kim, Hee Kyung Chang, Myunghee Kang, Yoon Jung Choi, Seung-Mo Hong, Soomin Ahn, Min Ju Kim, Mee Soo Chang, So-Young Jin
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
PURPOSE The most recent 2017 World Health Organization (WHO) classification of pancreatic neuroendocrine neoplasms (PanNENs) has refined the three-tiered 2010 scheme by separating grade 3 pancreatic neuroendocrine tumors (G3 PanNETs) from poorly diff
Autor:
Wei Chong, Yawen Zhao, Qiao Xu, Jinman Zhang, Zhifang Guo, Feng Gu, Yongjie Ma, Xiaoli Liu, Ying Shao, Huikun Zhang
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose Anterior gradient 3 (AGR3) belongs to human anterior gradient (AGR) family. The function of AGR3 on cancer remains unknown. This research aimed to investigate if AGR3 had prognostic values in invasive ductal carcinoma (IDC) of breast cancer a
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose Although cathepsin C (CTSC) has been reported to maintain malignant biological properties in various cancers, its functions in hepatocellular carcinoma (HCC) remain obscure. We aimed to investigate the potential role of CTSC in HCC. Materials
Autor:
Sardar Alam, Maria Trypaki, Dimitris Mavroudis, Vassilis Georgoulias, John Souglakos, Odysseas Zoras, Ippokratis Messaritakis, Maria Tzardi, Maria Sfakianaki, Chara Papadaki, Eleni Lagoudaki
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose The purpose of this study was to investigate the prognostic significance of liver kinase b1 (LKB1) loss in patients with operable colon cancer (CC). Materials and Methods Two hundred sixty-two specimens from consecutive patients with stage II
Autor:
Boram Park, Jae Young Joung, Weon Seo Park, Kang Hyun Lee, Jinsoo Chung, Sung-Han Kim, Ho Kyung Seo
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
PURPOSE The purpose of this study was to identify prognostic tissue markers for several survival outcomes after radical nephroureterectomy among patients with upper urinary tract urothelial carcinoma using tissue microarray and immunohistochemistry.
Autor:
Jin Haeng Chung, Kyu Sang Lee, Jong Seok Lee, Jin Won Kim, Keun Wook Lee, Soo Mee Bang, Yu Jung Kim, Junghoon Shin, Ji Won Kim, Ji Yun Lee, Se Hyun Kim, Jee Hyun Kim, Jeong Ok Lee, Koung Jin Suh
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
PURPOSE Programmed death-1 (PD-1)/PD-1 ligand (PD-L1) axis blockades have revolutionized the treatment of advanced non-small cell lung cancer (NSCLC). We assessed the effect of platinum-based chemotherapy on tumor PD-L1 expression and its clinical im
Autor:
Sung Bum Kang, Sumi Yun, Yoonjin Kwak, Duck Woo Kim, Hye Seung Lee, Soo Kyung Nam, An Na Seo, Heung Kwon Oh
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose Molecular treatments targeting epidermal growth factor receptors (EGFRs) are important strategies for advanced colorectal cancer (CRC). However, clinicopathologic implications of EGFRs and EGFR ligand signaling have not been fully evaluated.
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose Pembrolizumab, a programmed cell death protein 1 (PD1) inhibitor inhibits the interplay between PD1 of T-cell and programmed cell death ligand 1 (PDL1) on tumor cells. Although pembrolizumab has been tried to various subtypes of non-Hodgkin l