Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hisashi Yamada"'
Autor:
Ayako Suzuki, Nobuto Shibata, Koji Kasanuki, Tomoyuki Nagata, Shunichiro Shinagawa, Nobuyuki Kobayashi, Tohru Ohnuma, Yoshihide Takeshita, Eri Kawai, Toshiki Takayama, Kenya Nishioka, Yumiko Motoi, Nobutaka Hattori, Kazuhiko Nakayama, Hisashi Yamada, Heii Arai
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 6, Iss 1, Pp 90-97 (2016)
Background/Aims: Mutations in the presenilin 2 (PSEN2) gene cause familial Alzheimer's disease (AD). Common polymorphisms affect gene activity and increase the risk of AD. Nonsynonymous polymorphisms in the PSEN2 gene showed Lewy body dementia (LBD)
Externí odkaz:
https://doaj.org/article/6442245d32674aca9f0f80089e02ac8a
Autor:
Tomoyuki Nagata, Nobuyuki Kobayashi, Jumpei Ishii, Shunichiro Shinagawa, Ritsuko Nakayama, Nobuto Shibata, Bolati Kuerban, Tohru Ohnuma, Kazuhiro Kondo, Heii Arai, Hisashi Yamada, Kazuhiko Nakayama
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 5, Iss 1, Pp 64-73 (2015)
Background/Aims: In the present study, we examined whether DNA methylation of the brain-derived neurotrophic factor (BDNF) promoter is associated with the manifestation and clinical presentation of Alzheimer's disease (AD). Methods: Of 20 patients wi
Externí odkaz:
https://doaj.org/article/bcba0903cbb54d52b808c08d8579e73d
Autor:
Tomoyuki Nagata, Nobuto Shibata, Shunichiro Shinagawa, Ritsuko Nakayama, Bolati Kuerban, Tohru Ohnuma, Heii Arai, Kazuhiko Nakayama, Hisashi Yamada
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 3, Iss 1, Pp 272-280 (2013)
Background: Some polymorphisms of the neurotrophin family have previously been investigated as candidate genes for Alzheimer's disease (AD). In the present study, we examined whether neurotrophin-3 (NTF-3) polymorphisms are genetic risk factors in pa
Externí odkaz:
https://doaj.org/article/c67bb0cf6aab44a39790874fd91665f5
Autor:
Tomoyuki Nagata, Shunichiro Shinagawa, Bolati Kuerban, Nobuto Shibata, Tohru Ohnuma, Heii Arai, Kazuhiko Nakayama, Hisashi Yamada
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 3, Iss 1, Pp 66-73 (2013)
Aims: In the present study, we investigated whether apolipoprotein E (APOE) polymorphisms influenced the cognitive function of Japanese patients with Alzheimer's disease (AD) at certain ages. Methods: Among 200 outpatients with dementia and amnestic
Externí odkaz:
https://doaj.org/article/cc7c9b77da48438d8027de5ca5f8d7a3