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Publikováno v:
Journal of Cellular and Molecular Medicine
The cell division cycle associated 8 (CDCA8) is a crucial component of the chromosome passenger complex (CPC). It has been implicated in the regulation of cell dynamic localization during mitosis. However, its role in hepatocellular carcinoma (HCC) i
Autor:
Michael Z. Zulu, Ilhem Messaoudi, James D. Brien, Alexandria Dickson, Neil Tedeschi, Richard H. Scheuermann, Tara L. Steffen, Delia F. Tifrea, Kevin J. Maroney, Sarah L. George, Amelia K. Pinto, Yun Zhang, Amanda N. Pinski
Publikováno v:
Journal of Leukocyte Biology
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is the causative agent of coronavirus disease‐2019 (COVID‐19), a respiratory disease that varies in severity from mild to severe/fatal. Several risk factors for severe disease have
Autor:
Maryam Salimi, Mohammad Mahdi Majidi, Elham Roshandel, Sarvenaz Samadi Kochaksaraei, Abbas Hajifathali, Farshid Alaeddini, Sepide Kazemi, Nasser Aghdami, Behnam Sadeghi, Olle Ringdén, Ali Pirsalehi, Hoda Sadrosadat, Ghazaleh Sankanian
Publikováno v:
Journal of Cellular and Molecular Medicine
Acute respiratory distress syndrome (ARDS) is the most common cause of death in COVID‐19 patients. The cytokine storm is the main driver of the severity and magnitude of ARDS. Placenta‐derived decidua stromal cells (DSCs) have a stronger immunosu
Publikováno v:
Journal of Cellular and Molecular Medicine
Previous studies have shown that microRNA‐206 (miR‐206) exhibits anti‐tumour properties in various tumours. Nevertheless, diagnostic significance of miR‐206 in oral cancer is still poorly known. Our research was carried out to explore the per
Publikováno v:
Journal of Cellular and Molecular Medicine
The tumour‐suppressive role of LINC00472 has been extensively reported in various human cancers such as lung, colon and ovarian cancers, yet its function in pancreatic cancer remains unidentified. Here, the current research aimed to explore the rol
Autor:
Xiangyang Zhu, Megan M. Ostlie, Kyra L. Jordan, Sabena M. Conley, Nattawat Klomjit, Lilach O. Lerman, Amir Lerman
Publikováno v:
Journal of Cellular and Molecular Medicine
Immune‐modulatory properties of adipose tissue‐derived mesenchymal stem/stromal cells (MSCs) might be susceptible to metabolic disturbances. We hypothesized that the immune‐modulatory function of MSCs might be blunted in obese human subjects. M
Autor:
Yang Liu, Zheng Chen, Wu Xianrui, Zhi zhao Chen, Feng-Jie Tang, Jun lin Liao, Jianda Zhou, Ke Cao, Jingjing Li, Zi zi Chen, Xiang Chen
Publikováno v:
Journal of Cellular and Molecular Medicine
Cutaneous melanoma (CM) is an aggressive cancer; given that initial and specific signs are lacking, diagnosis is often late and the prognosis is poor. RNA modification has been widely studied in tumour progression. Nevertheless, little progress has b
Autor:
Chen Jin, Zhifu Sun, Yifan Tong, Gang Chen, Bingren Hu, Tuo Deng, Jungang Zhao, Tan Zhang, Liming Deng, Zhehao Shi, Yi Wang
Publikováno v:
Journal of Cellular and Molecular Medicine
Ferroptosis is a newly identified cell death mechanism and potential biomarker for hepatocellular carcinoma (HCC) therapy; however, its clinical relevance and underlying mechanism remain unclear. In this study, transcriptome and methylome data from 3
Autor:
Xiao-kun Wang, Yawei Zhang, Wen‐Jie Zhou, Lyu‐jia Cheng, Yulong He, Changhua Zhang, Ming-yu Huo, Chunming Wang, Bo Li, Tian‐Zhi Zhang
Publikováno v:
Journal of Cellular and Molecular Medicine
N6‐methyladenosine (m6A) is a well‐known modification of RNA. However, as a key m6A methyltransferase, METTL16 has not been thoroughly studied in gastric cancer (GC). Here, the biological role of METTL16 in GC and its underlying mechanism was stu
Publikováno v:
Journal of Cellular and Molecular Medicine
Studies have demonstrated that circular RNAs (circRNAs) play important roles in various types of cancer; however, the mechanisms of circRNAs located in the nucleus have rarely been explored. Here, we report a novel circular RNA circPLCE1 (hsa_circ_00