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Autor:
Michael Z. Zulu, Ilhem Messaoudi, James D. Brien, Alexandria Dickson, Neil Tedeschi, Richard H. Scheuermann, Tara L. Steffen, Delia F. Tifrea, Kevin J. Maroney, Sarah L. George, Amelia K. Pinto, Yun Zhang, Amanda N. Pinski
Publikováno v:
Journal of Leukocyte Biology
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is the causative agent of coronavirus disease‐2019 (COVID‐19), a respiratory disease that varies in severity from mild to severe/fatal. Several risk factors for severe disease have
Autor:
Chi Liu, Leyuan Wang, Xiangping Qu, Ming Yang, Xizi Du, Lin Yuan, Gelei Xiao, Yang Xiang, Ling Qin, Kai Zhou, Huijun Liu, Wenkai Li, Xiaoqun Qin, Yu Yang
Publikováno v:
Journal of Cellular and Molecular Medicine
Respiratory syncytial virus (RSV) infection in airway epithelial cells is the main cause of bronchiolitis in children. Excessive mucus secretion is one of the primary symbols in RSV related lower respiratory tract infections (RSV‐related LRTI). How
Autor:
Paul Monagle, Sant-Rayn Pasricha, Vera Ignjatovic, Matthew D. Linden, Ashley P. Ng, Alison Farley, Samir Taoudi, Joseph Torresi
Publikováno v:
Immunology and Cell Biology
We hypothesize that thrombosis with thrombocytopenia syndrome recently described after administration of adenovirus‐vectored vaccines for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) occurs as a result of the unique properties o
Publikováno v:
Immunology and Cell Biology
Schistosomiasis is a widespread helminth disease that poses a heavy social and economic burden on people worldwide. Advanced schistosomiasis often develops into schistosome‐associated liver fibrosis, the pathogenesis of which remains unclear. This
Autor:
Chi Liu, Zhen Duan, Leyuan Wang, Ming Yang, Kai Zhou, Xizi Du, Mengping Wu, Lin Yuan, Yizhou Zou, Huijun Liu, Xiangping Qu, Mandie Liu, Yang Xiang, Yu Yang, Xiaoqun Qin
Publikováno v:
Journal of Cellular and Molecular Medicine
As the direct contacting site for pathogens and allergens, the mucosal barrier plays a vital role in the lungs and intestines. Innate lymphoid cells (ILCs) are particularly resident in the mucosal barrier and participate in several pathophysiological
Autor:
Yingzi Zhao, Fang Zong
Publikováno v:
Immunity, Inflammation and Disease
Immunity, Inflammation and Disease, Vol 9, Iss 4, Pp 1439-1446 (2021)
Immunity, Inflammation and Disease, Vol 9, Iss 4, Pp 1439-1446 (2021)
Background Pre‐eclampsia (PE) is mainly attributed to the inflammation of trophoblast cells in pregnant women, which results in damage to the maternal organs and growth retardation of the fetus. Alkaloid leonurine (LNR) is a plant compound and has
Publikováno v:
Immunity, Inflammation and Disease
Immunity, Inflammation and Disease, Vol 9, Iss 4, Pp 1306-1320 (2021)
Immunity, Inflammation and Disease, Vol 9, Iss 4, Pp 1306-1320 (2021)
Objective The aim of this study was to explore expression profiles of long noncoding RNA (lncRNA)‐messenger RNA (mRNA) in abdominal aortic aneurysm (AAA) patients. Further, we explored the mechanisms by which lncRNA SNHG5 modulates the function of
Autor:
Cayman Williams, Alan Kennedy, Shane Minogue, Neil Halliday, Erin Waters, David M. Sansom, Tie Zheng Hou, Behzad Rowshanravan, Daniel Janman, Claudia Hinze, Omar S. Qureshi
Publikováno v:
Immunology
CTLA‐4 is an essential regulator of T‐cell immune responses whose intracellular trafficking is a hallmark of its expression. Defects in CTLA‐4 trafficking due to LRBA deficiency cause profound autoimmunity in humans. CTLA‐4 rapidly internaliz
Publikováno v:
Journal of Leukocyte Biology
Immune cells such as T cells, macrophages, dendritic cells, and other immunoregulatory cells undergo metabolic reprogramming in cancer and inflammation‐derived microenvironment to meet specific physiologic and functional demands. Myeloid‐derived
Publikováno v:
Journal of Cellular and Molecular Medicine
Smoking and Candida albicans (C. albicans) infection are risk factors for many oral diseases. Several studies have reported a close relationship between smoking and the occurrence of C. albicans infection. However, the exact underlying mechanism of t