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Autor:
Steven F. Ziegler, Jana Gillies, Laura Cook, Shigeru Tanaka, Kyle T Reid, Danielle J. Smyth, Madeleine P. J. White, Elmeri Hakkinen, Qing Huang, Brett de Bie, May Q. Wong, Megan K. Levings, Rick M. Maizels
Publikováno v:
Immunology and Cell Biology
Immune homeostasis in the intestine is tightly controlled by FOXP3+ regulatory T cells (Tregs), defects of which are linked to the development of chronic conditions, such as inflammatory bowel disease (IBD). As a mechanism of immune evasion, several
Autor:
Olivier Hermine, Benoit Albaud, Laurent Frenzel, Sandra Mignot, Cécile Bally, Nicolas Cagnard, Justine Siavellis
Publikováno v:
Journal of Cellular and Molecular Medicine
In haemophilia, the recurrence of hemarthrosis leads to irreversible arthropathy termed haemophilic arthropathy (HA). However, HA is a unique form of arthropathy in which resident cells, such as fibroblast‐like synoviocytes (FLS), come into direct
Autor:
Rasmus Mortensen, Anne Ma Dyrhol-Riise, Nelita du Plessis, Synne Jenum, Kristian Tonby, Gerhard Walzl, Marthe Jøntvedt Jørgensen
Publikováno v:
Journal of Leukocyte Biology
Myeloid‐derived suppressor cells (MDSCs) increase in tuberculosis (TB) and may be targets for host‐directed therapy (HDT). In this study, we use flow cytometry to analyze the effects of cyclooxygenase‐2 inhibitors (COX‐2i) on monocytic (M)‐
Autor:
García-Bernal, D., Palomo, Marta, Martínez, C.M., Millán-Rivero, J.E., García-Guillén, A.I., Blanquer, M., Díaz-Ricart, M., Sackstein, R., Carreras, Enric, Moraleda, J.M., Universitat Autònoma de Barcelona
Publikováno v:
Journal of Cellular and Molecular Medicine
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Altres ajuts: This study has been funded by Josep Carreras Leukaemia Foundation (Grant 11R/2016 and 03R/2019). Allogeneic hematopoietic stem cell transplantation (allo-HCT) is an effective therapy for the treatment of high-risk haematological maligna
Publikováno v:
Immunological Reviews
Mohsen, Mona O.; Augusto, Gilles; Bachmann, Martin F. (2020). The 3Ds in virus-like particle based-vaccines: "Design, Delivery and Dynamics". Immunological reviews, 296(1), pp. 155-168. Wiley-Blackwell 10.1111/imr.12863
Mohsen, Mona O.; Augusto, Gilles; Bachmann, Martin F. (2020). The 3Ds in virus-like particle based-vaccines: "Design, Delivery and Dynamics". Immunological reviews, 296(1), pp. 155-168. Wiley-Blackwell 10.1111/imr.12863
Vaccines need to be rationally designed in order be delivered to the immune system for maximizing induction of dynamic immune responses. Virus‐like particles (VLPs) are ideal platforms for such 3D vaccines, as they allow the display of complex and
Autor:
Irene Soria, Mario Pérez-Diego, José Luis Subiza, Oscar Palomares, Cristina Benito-Villalvilla, Enrique Fernández-Caldas
Publikováno v:
Allergy
Background Polymerized allergoids conjugated to mannan (PM) are suitable vaccines for allergen‐specific immunotherapy (AIT). Alum remains the most widely used adjuvant in AIT, but its way of action is not completely elucidated. The better understan
Autor:
Makoto Takeda
Publikováno v:
Microbiology and Immunology
Spike (S) protein cleavage is a crucial step in coronavirus infection. In this review, this process is discussed, with particular focus on the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Compared with influenz
Publikováno v:
Annals of the New York Academy of Sciences
Peripheral blood hematopoietic stem and progenitor cells (HSPCs), mobilized by granulocyte colony‐stimulating factor, are widely used as a source for both autologous and allogeneic stem cell transplantation. The use of mobilized HSPCs has several a
Autor:
Ganesh R. Talekar, Jamie Y. Story, James DeGregori, Raira S. Ank, Christopher C. Porter, Miyoung Lee, Curtis J. Henry, Jamie A.G. Hamilton, Andrew Fedanov, Talia Sisroe, Charles A. Dinarello, Dov B. Ballak, Rae Hunter, Sunil S. Raikar, Elan Z. Eisenmesser
Publikováno v:
Aging Cell
Aging‐associated declines in innate and adaptive immune responses are well documented and pose a risk for the growing aging population, which is predicted to comprise greater than 40 percent of the world's population by 2050. Efforts have been made
Publikováno v:
Immunology
Upon activation, naïve CD4(+) T helper (Th) cells differentiate into distinct Th effector cell lineages depending on the local cytokine environment. However, these polarized Th cells can also adapt their function and phenotype depending on the chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc7fac886e685d7cc8024fb63989c3a
https://europepmc.org/articles/PMC8044333/
https://europepmc.org/articles/PMC8044333/