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Publikováno v:
Cell Proliferation
Acetaminophen (APAP) is a widely applied drug for the alleviation of pain and fever, which is also a dose‐depedent toxin. APAP‐induced acute liver injury has become one of the primary causes of liver failure which is an increasingly serious threa
Autor:
Kazunori Nakajima, Satoko Morishima, Yasuo Morishima, Minoko Takanashi, Koichi Kashiwase, Tetsuo Mori, Shunichi Kato, Fumihiro Azuma, Takeshi Orihara, Shunro Kai, Kayoko Matsumoto, Hiromasa Yabe, Koji Kato, Masahiro Satake, Toshio Yabe
Publikováno v:
Stem Cells Translational Medicine
Clinical application of induced pluripotent stem cells (iPS) in autologous settings has just begun. To overcome the high time and cost barriers in the individual production of autologous iPS, the use of allogeneic iPS with a homozygous human leukocyt
Autor:
Hao Wang, Yiming Zhao, Xiaoxi Xu, Grace Wang, Baoren Zhang, Ganggang Shi, Caigan Du, Shanzheng Lu, Xiang Li, Xu Lan
Publikováno v:
Stem Cells Translational Medicine
Endometrial regenerative cells (ERCs) are mesenchymal-like stromal cells, and their therapeutic potential has been tested in the prevention of renal ischemic reperfusion injury, acute liver injury, ulcerative colitis, and immunosuppression. However,
Publikováno v:
Stem Cells Translational Medicine
Stem cells translational medicine, vol 6, iss 10
Stem cells translational medicine, vol 6, iss 10
Summary The mission of the California Institute of Regenerative Medicine (CIRM) is to accelerate treatments to patients with unmet medical needs. In September 2016, CIRM sponsored a workshop held at the University of California, Los Angeles, to discu
Publikováno v:
Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 6, Iss 8, Pp 1661-1665 (2017)
Stem Cells Translational Medicine, Vol 6, Iss 8, Pp 1661-1665 (2017)
Summary Megakaryocytes (Mgks) are terminally differentiated blood cells specified to produce platelets, whereas hematopoietic stem cells (HSCs) are the most undifferentiated blood cells that retain multipotency to produce all kinds of blood cells. As
Autor:
Shih-Chieh Hung, Jir You Wang, Wei Ming Chen, Po Kuei Wu, Kuang Yu Chao, Cheng Fong Chen, Ming Chau Chang
Publikováno v:
Stem Cells Translational Medicine
Cell therapies using human mesenchymal stem cells (MSCs) have received much attention in the past decade. In pursuit of the therapeutic potential of MSCs, cell expansion is required to generate a great number of cells with desired phenotype and funct
Autor:
Joohyun Kim, Kwaku Bonsra, Je-Yoel Cho, Goo Jang, Hyunmin Cho, Byung-Jae Kang, Mincheol Choi, Hyun-Kyung Chang, Soo-Young Yum, So-Yeong Lee, Yiming Shen, Hyongbum Kim, Pyung-Hwan Kim
Publikováno v:
Stem Cells Translational Medicine
Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) exhibit potency for the regeneration of infarcted hearts. Vascular endothelial growth factor (VEGF) is capable of inducing angiogenesis and can boost stem cell-based therapeutic ef
Autor:
Elizabeth R. Sutton, David Mallinson, Olga de la Rosa, Wilfried Dalemans, Donald R. Dunbar, Eleuterio Lombardo, Susan Ridha
Publikováno v:
Stem Cells Translational Medicine
The ability to identify and stratify patients that will respond to specific therapies has been transformational in a number of disease areas, particularly oncology. It is anticipated that this will also be the case for cell-based therapies, particula
Autor:
Takeshi Harada, Michiko Kishida, Toshifumi Takao, Hideki Yamamoto, Akira Kikuchi, Shosei Kishida, Chihiro Awada
Publikováno v:
Cancer Science
Wnt5b is a member of the same family of proteins as Wnt5a, the overexpression of which is associated with cancer aggressiveness. Wnt5b is also suggested to be involved in cancer progression, however, details remain unclarified. We analyzed the bioche
Autor:
Bruno Manadas, Fábio G. Teixeira, Leo A. Behie, Krishna M. Panchalingam, Ana João Rodrigues, Miguel M. Carvalho, António J. Salgado, Bárbara Mendes-Pinheiro, Nuno Sousa, Sandra I. Anjo
Publikováno v:
Stem Cells Translational Medicine
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Research in the last decade strongly suggests that mesenchymal stem cell (MSC)-mediated therapeutic benefits are mainly due to their secretome, which has been proposed as a possible therapeutic tool for the treatment of Parkinson's disease (PD). Inde