Zobrazeno 1 - 10
of 125
pro vyhledávání: ''
Autor:
Jiangdong An, Bin Geng, Dacheng Zhao, Cuifang Wang, Xingwen Wang, Hong Wang, Yayi Xia, Shenghong Wang, Hua Han, Jinwen He
Publikováno v:
Journal of Cellular and Molecular Medicine
LncRNAs and microRNAs play critical roles in osteoblast differentiation and bone formation. However, their exact roles in osteoblasts under fluid shear stress (FSS) and the possible mechanisms remain unclear. The aim of this study was to explore whet
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 11, Iss 12, Pp 3218-3229 (2021)
FEBS Open Bio, Vol 11, Iss 12, Pp 3218-3229 (2021)
The changing extra‐ and intracellular microenvironment calls for rapid cell fate decisions that are precisely and primarily regulated at the transcriptional level. The cellular components of the immune system are excellent examples of how cells res
Publikováno v:
Journal of Cellular and Molecular Medicine
Gastric cancer (GC) is the most frequent digestive system malignant tumour and the second most common cause of cancer death globally. Cancer stem cell (CSC) is a small percentage of cancer cells in solid tumours that have differentiation, self‐rene
Autor:
Xavier Dubernard, Randa Belgacemi, Gaëtan Deslée, Jean-Claude Mérol, Christophe Ruaux, Valérian Dormoy, Zania Diabasana, Jeanne-Marie Perotin, Antony Hoarau, Myriam Polette
Publikováno v:
Journal of Cellular and Molecular Medicine
Journal of Cellular and Molecular Medicine, Wiley Open Access, 2021, ⟨10.1111/jcmm.16729⟩
Journal of Cellular and Molecular Medicine, Wiley Open Access, 2021, ⟨10.1111/jcmm.16729⟩
The alteration of the mucociliary clearance is a major hallmark of respiratory diseases related to structural and functional cilia abnormalities such as chronic obstructive pulmonary diseases (COPD), asthma and cystic fibrosis. Primary cilia and moti
Publikováno v:
Journal of Cellular and Molecular Medicine
CDR1as is a well‐identified circular RNA with regulatory roles in a variety of physiological processes. However, the effects of CDR1as on stemness of periodontal ligament stem cells (PDLSCs) and the underlying mechanisms remain unclear. In this stu
Autor:
Yasuhiro Takashima, Katsunori Semi
Publikováno v:
Development, Growth & Differentiation
Forty years have passed since the first pluripotent stem cells (PSCs), mouse embryonic stem cells (ESCs), were established. Since then, several PSCs have been reported, including human ESCs in 1998, mouse epiblast stem cells (EpiSCs) in 2007, induced
Publikováno v:
Journal of Cellular and Molecular Medicine
Osteoporosis is a metabolic disease that results from oxidative stress or inflammation in renal disorders. microRNAs (miRNAs) are recently implicated to participate in osteoporosis, but the mechanism remains largely unexplored. Herein, we aimed to ex
Autor:
Xiaodong Bai, Hua Gao, Baojun Wang, Yadong Li, Wentao Chen, Liang Zhao, Yijun Wang, Zhenyu Liu
Publikováno v:
Journal of Cellular and Molecular Medicine
This study explored the therapeutic effect of bone marrow mesenchymal stem cell‐derived exosomes on the treatment of obesity‐induced fracture healing. Quantitative real‐time PCR was used to detect the expression of lncRNA H19, miR‐467 and Hox
Publikováno v:
Journal of Cellular and Molecular Medicine
Previous studies in Graves’ orbitopathy (GO) patient‐derived fibroblasts showed that inhibition of autophagy suppresses adipogenic differentiation. Autophagy activation is associated with inflammation, production of reactive oxygen species and fi
Autor:
Hideyuki Okano, Kent Imaizumi
Publikováno v:
Development, Growth & Differentiation
Pluripotent stem cells (PSCs) can differentiate into all cell types in the body, and their differentiation procedures recapitulate the developmental processes of embryogenesis. Focusing on neurodevelopment, we describe here the application of knowled