Zobrazeno 1 - 10
of 20
pro vyhledávání: '"35"'
Autor:
Baoyue Zhang, Shaojia Huang, Yi Jiang, Yangbo Hu, Wei Zhou, Bin Liu, Wei Shi, Abigail Schammel
Publikováno v:
EMBO J
In bacteria, σ(28) is the flagella‐specific sigma factor that targets RNA polymerase (RNAP) to control the expression of flagella‐related genes involving bacterial motility and chemotaxis. However, the structural mechanism of σ(28)‐dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50078d19ead5dcabe116f40baf788530
https://europepmc.org/articles/PMC7360974/
https://europepmc.org/articles/PMC7360974/
Publikováno v:
International Journal of Cancer
Gain‐of‐function mutations of KIT are pathognomonic in sporadic gastrointestinal stromal tumors (GISTs). Several microRNAs have been shown to be dysregulated in GISTs and impact KIT expression. Little is known though on KIT‐independent targets
Autor:
Xavier Robellet, Pascal Bernard, Esther Toselli-Mollereau, Christian H. Haering, Emilie Chautard, Lydia Fauque, Carlo Klein, Léo Mouillard, Lia N'Guyen, Sébastien Lemaire, Pénélope Legros, Clémence Hocquet, Christoph Schiklenk, Didier Auboeuf
Publikováno v:
EMBO Journal
EMBO Journal, EMBO Press, 2016, 35 (14), pp.1565-1581. ⟨10.15252/embj.201592849⟩
EMBO Journal, 2016, 35 (14), pp.1565-1581. ⟨10.15252/embj.201592849⟩
EMBO Journal, EMBO Press, 2016, 35 (14), pp.1565-1581. ⟨10.15252/embj.201592849⟩
EMBO Journal, 2016, 35 (14), pp.1565-1581. ⟨10.15252/embj.201592849⟩
Condensins associate with DNA and shape mitotic chromosomes. Condensins are enriched nearby highly expressed genes during mitosis, but how this binding is achieved and what features associated with transcription attract condensins remain unclear. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305c2071295750b6a7326f74ce943e95
https://europepmc.org/articles/PMC4946138/
https://europepmc.org/articles/PMC4946138/
Autor:
Pranil Raut, Meng Chen, Cecile T.J. Holweg, Kirk V. Shepard, Ming Yang, Eugene Choo, Hooman Pazwash
Publikováno v:
Clinical and Experimental Allergy
Background Current biologic therapies target allergic, eosinophilic or type 2 inflammation phenotypic asthma. However, frequency and degree of overlap among these subtypes is unclear. Objective To characterize overlap among allergic, eosinophilic and
Autor:
Mengyue Niu, Fanpeng Zhao, Karina S. Bondelid, Hisashi Fujioka, Wenzhang Wang, Jun Liu, Sandra L. Siedlak, Sandy Torres, Xiongwei Zhu
Publikováno v:
Aging Cell
D620N mutation in the vacuolar protein sorting 35 ortholog (VPS35) gene causes late‐onset, autosomal dominant familial Parkinson's disease (PD) and contributes to idiopathic PD. However, how D620N mutation leads to PD‐related deficits in vivo rem
Autor:
Jose-Andres C. Portillo, Jin‐Sang Yu, Carlos S. Subauste, Samuel Hansen, M. Cecilia Subauste, Timothy S. Kern
Publikováno v:
The FASEB Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol 35, iss 3
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol 35, iss 3
While the administration of anti‐CD154 mAbs in mice validated the CD40‐CD154 pathway as a target against inflammatory disorders, this approach caused thromboembolism in humans (unrelated to CD40 inhibition) and is expected to predispose to opport
Publikováno v:
Food Science & Nutrition
Food Science & Nutrition, 7(4):1482-1493
Food Science & Nutrition, 7(4):1482-1493
Clinacanthus nutans (Burm. f.) Lindau (C. nutans) has been reported to lower blood glucose level; however, evidence on its efficacy in lowering diabetic complications is limited. The antidiabetic properties of C. nutans aqueous leaf extract on serum
Autor:
Shintaro Iwama, Yutaka Fujiwara, Aya Kuchiba, Noboru Yamamoto, Naoya Yamazaki, Yuichiro Ohe, Shiro Kimbara, Ken Ohashi, Shigehisa Kitano, Hiroshi Arima
Publikováno v:
Cancer Science
Thyroid dysfunction (TD) induced by immune checkpoint inhibitors is not sufficiently understood. The purpose of this retrospective observational study was to identify risk factors and the clinical course of TD induced by nivolumab. Patients with adva
Publikováno v:
American Journal of Reproductive Immunology
Problem Premature ovarian insufficiency (POI) imposes great challenge on female reproduction. Whether immune disturbance in ovarian environment was implicated in POI remains unclear. We aimed to characterize the cytokine profile in follicular fluid (
Publikováno v:
Journal of Cellular and Molecular Medicine
We carried out this meta‐analysis to explore the influence of paraoxonase 1 activity on the susceptibility of diabetes mellitus (DM), diabetic macroangiopathy and diabetic microangiopathy. Relevant studies were identified from PubMed, Web of Scienc