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Autor:
Kenichi Kaseno, Yoshitomo Fukuoka, Naoki Amaya, Hiroyasu Uzui, Hiroshi Tada, Kentaro Ishida, Hiroyuki Ikeda, Tetsuji Morishita
Publikováno v:
Internal Medicine
Objective Circulating endothelial progenitor cells (EPCs) are regulated by stromal cell-derived factor-1alpha (SDF-1α) and are reduced in type 2 diabetes mellitus (DM). SDF-1α is a substrate of dipeptidyl-peptidase-4 (DPP-4), so we investigated whe
Autor:
Motofumi Sasaki, Ken-ichiro Tanaka, Masakazu Notsu, Yuko Tada, Toshitsugu Sugimoto, Ippei Kanazawa, Nobuaki Kiyohara
Publikováno v:
Internal Medicine. 55:1275-1278
Objective We herein conducted a retrospective study to evaluate the long-term efficacy and safety of sitagliptin treatment in elderly patients with type 2 diabetes mellitus. Methods We analyzed the changes in glycemic control in 112 Japanese type 2 d
Autor:
Lei Song, Yubao Zou, Yuejin Yang, Hui Dong, Xiongjing Jiang, Haiying Wu, Runlin Gao, Huimin Zhang, Meng Peng
Publikováno v:
Internal Medicine. 55:9-14
Objective To compare the nephrotoxicity of iodixanol in elderly patients who underwent a renal artery intervention (RAI) with those who underwent an other peripheral vascular intervention (OPI). Methods Three hundred fifty-four consecutive patients (
Publikováno v:
Internal Medicine. 54:1711-1715
Objective The aim of this study was to assess the safety and efficacy of lenalidomide (Len), with the dose adjusted according to the renal function, plus low-dose dexamethasone (Dex) in older patients with bortezomib (Bor)-resistant multiple myeloma
Autor:
Hidetsuna Watanabe, Koichi Miyaki, Akira Kimura, Takashi Kawamura, Masashi Goto, Yuko Takahashi, Satoe Okabayashi, Manabu Musashi, Setsuko Taneichi, Reiko Uruma
Publikováno v:
Internal Medicine. 53:949-956
Objective Kakkonto, a Japanese herbal medicine, is frequently used to treat the common cold not only with a physician's prescription, but also in self-medication situations. This study aimed to examine whether Kakkonto prevents the aggravation of col
Autor:
Kunihiro Asanuma, Yuki Kamimoto, Kohshi Ohishi, Yoshiki Yamashita, Kanako Saito, Takeshi Matsumoto, Naoyuki Katayama, Hideo Wada, Hideki Nomura, Norikazu Yamada, Toshiro Mizuno, Masanobu Usui
Publikováno v:
Internal Medicine. 53:413-419
Objective Many patients with malignant diseases are frequently complicated with some type of thrombosis, such as venous thromboembolism (VTE) or disseminated intravascular coagulation (DIC). Methods This retrospective study was designed to examine th
Autor:
Tomonori Itoh, Toshiaki Sakai, Masanobu Niiyama, Motoyuki Nakamura, Osamu Nishiyama, Yuji Suzuki
Publikováno v:
Internal Medicine. 53:717-720
A 42-year-old woman with a history of aspirin-induced asthma was admitted with severe chest pain. Emergency coronary angiography revealed coronary artery spasms. The administration of vasodilators did not suppress the anginal symptoms, and the differ
Autor:
Takuro Sakagami, Junichiro James Kazama, Ichiei Narita, Hiroshi Moriyama, Toshinori Takada, Katsuaki Asakawa, Eiichi Suzuki
Publikováno v:
Internal Medicine. 53:1921-1926
Objective Direct hemoperfusion with polymyxin B-immobilized fiber columns (PMX-DHP) has been used for the treatment of septic shock. It was recently suggested that PMX-DHP may also be effective in acute exacerbations of idiopathic pulmonary fibrosis
Autor:
Nobuhiro Tanabe, Jiro Terada, Koichiro Tatsumi, Toshihiko Sugiura, Osamu Yokosuka, Akira Naito, Seiichiro Sakao, Tatsuo Kanda
Publikováno v:
Internal Medicine. 53:771-775
A 48-year-old woman was diagnosed with idiopathic pulmonary arterial hypertension (PAH) and administered PAH-specific therapies, including bosentan. Four years after the initiation of treatment with bosentan, liver dysfunction appeared, and ambrisent
Autor:
Kunihiro Ichinose, Tomoki Origuchi, Shigeru Kohno, Atsushi Kawakami, Yoshikazu Nakashima, Naoki Iwamoto, Hideki Nakajima, Yoshiro Horai, Takahisa Suzuki, Satoru Oka, Koichi Izumikawa, Hideki Nakamura, Shin-ya Kawashiri, Mami Tamai
Publikováno v:
Internal Medicine. 53:1023-1027
We herein report the case of a 21-year-old woman with refractory adult-onset Still's disease who developed central venous catheter-related methicillin-resistant Staphylococcus aureus sepsis during aggressive immunosuppressive therapy. She subsequentl