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Publikováno v:
Journal of Atherosclerosis and Thrombosis
Aim: Probucol is a controversial drug to inhibit ATP-binding cassette transporter A1 (ABCA1) and to exhibit some positive clinical effects such as regression of xanthomas. It reportedly rescues female infertility in scavenger receptor BI-deficient mi
Autor:
Ernst J. Schaefer, Masumi Ai, Yasuki Ito, Eiichiro Kanda, Hung Hsu, Powen Hsu, Ming-Hui Cheng
Publikováno v:
Journal of Atherosclerosis and Thrombosis
Aims: Prediabetes and diabetes are associated with increased insulin resistance and decreased insulin production, dyslipidemia, and increased cardiovascular disease (CVD) risk. Our goals were to assess lipoprotein subfractions using novel assays in s
Autor:
Lung Chan, Sheng-Feng Lin, Shinn-Kuang Lin, Yu-Te Lin, Han-Hwa Hu, Jiunn-Tay Lee, Yu Sun, Ruey-Tay Lin, Chyi Huey Bai, Cheng-Yu Wei, Yung-Yang Lin, Chih Hung Chen, Huey-Juan Lin, Po Lin Chen, A-Ching Chao
Publikováno v:
Journal of Atherosclerosis and Thrombosis
Aim: Although a lower level of non-high-density lipoprotein cholesterol (HDL-C) was reported to be inversely associated with spontaneous intracranial hemorrhage (ICH), no enough evidence has verified whether lipid profiles modify hemorrhagic transfor
Autor:
Ichiro Tatsuno, Yasuhiro Watanabe, Shoko Nakamura, Hidetoshi Kawana, Takashi Yamaguchi, Masahiro Ohira, Daiji Nagayama, Sho Tanaka, Atsuhito Saiki, Yuta Sato, Naomi Shimizu, Rena Oka, Haruki Imamura, Kohji Shirai
Publikováno v:
Journal of Atherosclerosis and Thrombosis
Aim Cardio-ankle vascular index (CAVI) reflects arterial stiffness and has been established as a useful surrogate marker of atherosclerosis. Contrary to the abundant data indicating slower progression of atherosclerosis with statins, studies on fibra
Autor:
Tetsuya Ishikawa, Isao Taguchi, Takatomo Nakajima, Itaru Hisauchi, Makoto Ayaori, Yukiko Mizutani, Katsunori Ikewaki, Tomoaki Ukaji, Yuri Koshikawa, Makoto Mutoh, Harumi Uto-Kondo, Hidehiko Nakamura
Publikováno v:
Journal of Atherosclerosis and Thrombosis
Aim: We examined the impact of baseline high-density lipoprotein cholesterol efflux capacity (CEC) on major cardiac adverse events (MACE) in patients with coronary artery disease (CAD) during a long-term secondary prevention. Method: CEC was measured
Autor:
Eiichi Araki, Koutaro Yokote, Hidenori Arai, Hideki Suganami, Shizuya Yamashita, Shun Ishibashi
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 25:521-538
AIM To verify the superiority of pemafibrate over placebo and the non-inferiority of pemafibrate to the maximum dose of fenofibrate for determining the percent change in fasting serum triglyceride (TG) levels and to investigate safety by assessing th
Publikováno v:
Journal of Atherosclerosis and Thrombosis
Aim: Evaluation of serum lipoprotein profiles including triglyceride (TG)-rich lipoprotein, that is, intermediate-density lipoprotein (IDL), very low-density lipoprotein (VLDL), and chylomicron (CM) remnant is important to manage coronary heart disea
Autor:
Tomohiro Komatsu, Yoshinari Uehara
Publikováno v:
Journal of Atherosclerosis and Thrombosis
Autor:
Seimi Satomi-Kobayashi, Tatsuro Ishida
Publikováno v:
Journal of Atherosclerosis and Thrombosis
Aims: We evaluated whether exercised-based cardiac rehabilitation (CR) can ameliorate the HDL function, i.e., cholesterol efflux capacity (CEC) and paraoxonase-1 activity in patients with acute coronary syndrome (ACS). Methods: This study is a retros
Autor:
Tsutomu Hirano, Shinichi Mashiba, Shiho Kojima, Hirokazu Honda, Takanori Shibata, Masashi Ueda, Tetsuo Michihata, Yasuyuki Hayase
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 23:81-94
Aim Chronic kidney disease (CKD) may lead to reduced concentrations of high-density lipoprotein (HDL) and its subfractions (HDL2 and HDL3), and damage them via inflammation and oxidative stress. The present study aimed to determine the contribution o