Zobrazeno 1 - 10
of 53
pro vyhledávání: ''
Autor:
Takehiko Morishita, Toyoshige Endo, Tadashi Noguchi, Haruo Seto, Kumiko W. Shimotohno, Tomomi Hidaka
Publikováno v:
The Journal of Antibiotics. 52:429-432
Autor:
Takeo Yoshioka, Tsutomu Sawa, Naoki Matsumoto, Tomio Takeuchi, Masaaki Ishizuka, Shin-Ichi Hirano, Hironobu Iinuma
Publikováno v:
The Journal of Antibiotics. 50:906-911
The anti-arthritic effects of epoxyquinomicins on type II collagen-induced arthritis in DBA/1J mice were examined. Prophylactic treatment with epoxyquinomicins A, B, C and D (1-4 mg/kg) had potent inhibitory effects on type II collagen-induced arthri
Publikováno v:
The Journal of Antibiotics. 49:91-94
Leustroducsin B (LSN-B), a novel colony-stimulating factor (CSF) inducer produced by an actinomycetes, has previously been shown to induce CSF production in bone marrow stromal cells. To determine the biological activity of LSN-B on hematopoiesis in
Autor:
Takayuki Usui, Seiji Shibahara, Tsutomu Tsuruoka, Miyuki Ishii, Harumi Fukuyasu, Shigeharu Inouye
Publikováno v:
The Journal of Antibiotics. 49:155-161
The antimetastatic activity of ten compounds structurally related to nojirimycin A was examined using a pulmonary metastatic model of mouse B16 melanoma. Nojirimycin B, deoxynojirimycin, D-gluco-delta-lactam, CP3068 and CP3069 are structural analogue
Publikováno v:
The Journal of Antibiotics. 48:321-325
Cytogenin recovered the reduced mitogenic response to Con A of spleen cells of tumor bearing mice in vitro. The suppressive factor(s) was detected in adherent cell population in spleen cells. The reduced antitumor effector activity of spleen cells ta
Autor:
Tsuneaki Hida, Masayuki Takizawa, Akiko Hiramoto, Takashi Horiguchi, Seiichi Tanida, Setsuo Harada
Publikováno v:
The Journal of Antibiotics. 48:579-588
The microbial lipopeptides, TAN-1511 A, B and C, were isolated from the culture broth of Streptosporangium amethystogenes subsp. fukuiense AL-23456. Their structures were elucidated on the basis of their reactions and spectroscopic analyses. These li
Autor:
Li-Ping Chang, Maredith Arcuri, Richard R. Wang, Patricia M. Rose, Yue-Zhong Shu, Kin Sing Lam, Dolores M. Pirnik, Michael R. Kozlowski
Publikováno v:
The Journal of Antibiotics. 47:1328-1332
Autor:
Isao Kaneko, Hiroko Miyaoka, Akio Torikata, Akio Shiraishi, Masatoshi Inukai, Takafumi Kohama
Publikováno v:
The Journal of Antibiotics. 46:1494-1502
A new screening method for inducers of colony-stimulating factors (CSFs) was established using KM-102, a human bone marrow stromal cell line as the producer. In this method, the assay system which uses CSF dependent cell lines is combined with the CS
Autor:
Atsuko Hemmi, Masako Kinoshita, Kouhei Furuya, Kiyoshi Hamano, Kazuhiko Tanzawa, Yasuyuki Takamatsu, Masaaki C O Sankyo Co Miyamoto
Publikováno v:
The Journal of Antibiotics. 45:899-905
A new calcium blocker, designated leualacin, has been isolated from Hapsidospora irregularis. The compound inhibits the binding of 3H-nitrendipine, a well known synthetic calcium blocker, to cardiac Ca channel in a competitive manner, although its st
Publikováno v:
The Journal of Antibiotics. 44:441-444
Pharmacokinetic properties of WF-3681 and FR-62765 in rats were examined. FR-62765 showed higher peak concentrations in the plasma and higher concentrations in the sciatic nerve than WF-3681 when each compound was administered orally to rats. We ther