Zobrazeno 1 - 10
of 1 331
pro vyhledávání: ''
Autor:
Chen, Panpan, Tian, Jingyu, Zhou, Yanying, Chen, Yixin, Zhang, Huizhen, Jiao, Tingying, Huang, Min, Zhang, Hui, Huang, Peng, Yu, Ai-Ming, Gonzalez, Frank J, Bi, Huichang
Publikováno v:
International journal of biological sciences, vol 19, iss 7
Cellular senescence is a state of proliferative arrest, and the development of carcinoma can be suppressed by conferring tumor cell senescence. Recently, we found that carnitine palmitoyltransferase 1C (CPT1C) controls tumor cell proliferation and se
Autor:
Zhang, Juan, Luan, Zhi-Lin, Huo, Xiao-Kui, Zhang, Min, Morisseau, Christophe, Sun, Cheng-Peng, Hammock, Bruce D, Ma, Xiao-Chi
Publikováno v:
International journal of biological sciences, vol 19, iss 1
Acute kidney injury (AKI) is a pathological condition characterized by a rapid decrease in glomerular filtration rate and nitrogenous waste accumulation during hemodynamic regulation. Alisol B, from Alisma orientale, displays anti-tumor, anti-complem
Publikováno v:
International Journal of Biological Sciences. 19:104-119
Everolimus was designed as a mammalian target of rapamycin (mTOR) inhibitor. It has been proven as a targeted drug for gastric cancer (GC) therapy. However, long-term treatment with everolimus may cause severe side effects for recipients. Decreasing
Autor:
Meng-Ran, Li, Chun-Tao, Lei, Hui, Tang, Xing-Jie, Yin, Zhe, Hao, Yang, Qiu, Ya-Ru, Xie, Jie-Yu, Zeng, Hua, Su, Chun, Zhang
Publikováno v:
International Journal of Biological Sciences. 18:1896-1911
Publikováno v:
International Journal of Biological Sciences. 18:4400-4413
Endometriosis remains a common but challenging gynecological disease among reproductive-aged women with an unclear pathogenesis and limited therapeutic options. Numerous pieces of evidence suggest that NF-κB signaling, a major regulator of inflammat
Autor:
Yangyang, Yue, Kaijie, Wu, Weikun, Qian, Zeen, Zhu, Simei, Zhang, Wunai, Zhang, Weifan, Zhang, Shuai, Wu, Li, Li, Zheng, Wu, Qingyong, Ma, Keping, Xie, Zheng, Wang
Publikováno v:
International Journal of Biological Sciences. 18:4245-4259
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a high incidence of metastasis and dismal prognosis. As a member of Gas-Gap gene, RASAL2 is involved in the hydrolysis of RAS-GTP to RAS-GDP and abnormal expression in human cancers. Here we
Autor:
Jie Zhang, Weilong Zhong, Simin Zhou, Xiaoyi Wang, Jingwen Zhao, Man Liu, Lu Zhang, Lu Zhou, Xin Liu, Bangmao Wang, Hongxia Zhang
Publikováno v:
International Journal of Biological Sciences
Autoimmune hepatitis (AIH) is an immune-mediated chronic inflammatory liver disease, and its pathogenesis is not fully understood. Our previous study discovered that receptor interacting protein kinase 3 (RIP3) is correlated with serum transaminase l
Autor:
Yuling, Tang, Lei, Dong, Chong, Zhang, Xiubin, Li, Rongyu, Li, Huisang, Lin, Yini, Qi, Mingchuan, Tang, Yanli, Peng, Chuan, Liu, Jian, Zhou, Ning, Hou, Wenjia, Liu, Guan, Yang, Xiao, Yang, Yan, Teng
Publikováno v:
International Journal of Biological Sciences. 18:4329-4340
Previous studies have demonstrated the
Publikováno v:
International Journal of Biological Sciences. 18:1663-1676
Colon cancer (CC) is one of the most common malignances in digestive tract. M2-polarized macrophages within the tumor microenvironment could facilitate CC cell growth by transferring molecules via extracellular vesicles, but the mechanisms are not fu
Autor:
Diyuan, Zhou, Yizhou, Yao, Liang, Zong, Guoqiang, Zhou, Min, Feng, Junjie, Chen, Ganggang, Liu, Guoliang, Chen, Kang, Sun, Huihui, Yao, Yu, Liu, Xinyu, Shi, Weigang, Zhang, Bo, Shi, Qingliang, Tai, Guanting, Wu, Liang, Sun, Wenqing, Hu, Xinguo, Zhu, Songbing, He
Publikováno v:
International Journal of Biological Sciences. 18:3374-3389
Intestinal inflammation is a vital precipitating factor of colorectal cancer (CRC), but the underlying mechanisms are still elusive. TANK-binding kinase 1 (TBK1) is a core enzyme downstream of several inflammatory signals. Recent studies brought the