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Publikováno v:
International Journal of Biological Sciences. 18:1663-1676
Colon cancer (CC) is one of the most common malignances in digestive tract. M2-polarized macrophages within the tumor microenvironment could facilitate CC cell growth by transferring molecules via extracellular vesicles, but the mechanisms are not fu
Autor:
Wu, Wu, Qujin, Li, Zhu, Zhu, Chunming, Li, Peilin, Lu, Xi, Zhou, Yujing, Huang, Yan, Liu, Menghao, Wang, Jianping, Gong
Publikováno v:
International Journal of Biological Sciences. 18:3777-3794
Competing endogenous RNAs (ceRNAs) are a newly discovered class of molecular regulators involved in many diseases, especially tumors. Therefore, exploration of the potential ceRNA regulatory network regarding the occurrence and development of pancrea
Autor:
Yan-Ming, Liu, Yue, Cao, Ping-Sen, Zhao, Liang-Yin, Wu, Ya-Min, Lu, Yu-Long, Wang, Jia-Feng, Zhao, Xin-Guang, Liu
Publikováno v:
International Journal of Biological Sciences
Background: Circular RNAs (circRNAs), which generally act as microRNA (miRNA) sponges to competitively regulate the downstream target genes of miRNA, play an essential role in cancer biology. However, few studies have been reported on the role of cir
Autor:
Jiahui, Jiang, Qiao, Tang, Jiaoe, Gong, WeiHong, Jiang, Yiting, Chen, Qi, Zhou, Alaa, Aldeen, Shuanglian, Wang, Chengmin, Li, Wuwu, Lv, Tao, Du, Xingwei, Wang, Xueying, Long, Xueping, Feng
Publikováno v:
International Journal of Biological Sciences. 18:1878-1895
The biological functions of exosomes and microRNAs (miRs) in nasopharyngeal carcinoma (NPC) remain largely unexplored. Here, miR-197-3p was screened and identified, and whose level was reduced in serum and exosomes of patients with NPC. MiR-197-3p mi
Autor:
Pengpeng, Liu, Qiu, Zhong, Youai, Song, Deliang, Guo, Dong, Ma, Baiyang, Chen, Jianwei, Lan, Quanyan, Liu
Publikováno v:
International Journal of Biological Sciences. 18:2932-2948
Long noncoding RNAs (lncRNAs) play an important role in the progression of hepatocellular carcinoma (HCC). Linc01612 is a novel lncRNA that function remains unknown in the progression of cancers, including HCC. In this study, we discovered that Linc0
Autor:
Huixin, Zhou, Xiaolu, Huang, Xiang, Yang, Feng, Jiang, Fanggui, Shao, Wenjing, Shi, Kate, Huang, Jingjing, Pan, Yan, Zhang, Jie, Chen, Yumin, Wang
Publikováno v:
International Journal of Biological Sciences. 18:2116-2131
Lung adenocarcinoma (LAD) is a common malignancy; however, its underlying molecular mechanism is unclear. Circular RNAs (circRNAs) serve as significant cancer regulators. The overexpression of circRAPGEF5 in LAD tissues and cells indicated that it ma
Publikováno v:
International Journal of Biological Sciences. 18:1220-1237
Autor:
Xiangyu, Zhang, Feiyu, Chen, Peiran, Huang, Xinyu, Wang, Kaiqian, Zhou, Cheng, Zhou, Lei, Yu, Yuanfei, Peng, Jia, Fan, Jian, Zhou, Zuohua, Lu, Jie, Hu, Zheng, Wang
Publikováno v:
International Journal of Biological Sciences. 18:2249-2260
Hepatocellular carcinoma (HCC) is a major cause of cancer-related death worldwide. Although it has been known that hepatic stellate cells (HSCs) play critical roles in the development and progression of HCC, the molecular mechanism underlying crossta
Autor:
Xiaomin, Liu, Xianyi, Wang, Binshu, Chai, Zong, Wu, Zhitao, Gu, Heng, Zou, Hui, Zhang, Yanli, Li, Qiangling, Sun, Wentao, Fang, Zhongliang, Ma
Publikováno v:
International Journal of Biological Sciences. 18:4187-4202
Lung cancer is one of the deadliest cancers, in which non-small cell lung cancer (NSCLC) accounting for 85% and has a low survival rate of 5 years. Dysregulation of microRNAs (miRNAs) can participate in tumor regulation and many major diseases. In th
Autor:
Yan Fang, Rongzhang Dou, Sihao Huang, Lei Han, Hang Fu, Chaogang Yang, Jialin Song, Jinsen Zheng, Xinyao Zhang, Keshu Liu, Zhenxian Xiang, Xinghua Zhang, Shuyi Wang, Bin Xiong
Publikováno v:
International Journal of Biological Sciences. 18:3082-3101
Gastric cancer is anatomically proximal to peritoneum. Gastric cancer peritoneal metastasis is a complex biological process which is corresponded with disharmony within dysfunctional adipose tissue and metabolism reprogramming. Laminin gamma 1 (LAMC1