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of 326
pro vyhledávání: ''
Autor:
Meng-Ran, Li, Chun-Tao, Lei, Hui, Tang, Xing-Jie, Yin, Zhe, Hao, Yang, Qiu, Ya-Ru, Xie, Jie-Yu, Zeng, Hua, Su, Chun, Zhang
Publikováno v:
International Journal of Biological Sciences. 18:1896-1911
Publikováno v:
International Journal of Biological Sciences. 18:4400-4413
Endometriosis remains a common but challenging gynecological disease among reproductive-aged women with an unclear pathogenesis and limited therapeutic options. Numerous pieces of evidence suggest that NF-κB signaling, a major regulator of inflammat
Autor:
Jie Zhang, Weilong Zhong, Simin Zhou, Xiaoyi Wang, Jingwen Zhao, Man Liu, Lu Zhang, Lu Zhou, Xin Liu, Bangmao Wang, Hongxia Zhang
Publikováno v:
International Journal of Biological Sciences
Autoimmune hepatitis (AIH) is an immune-mediated chronic inflammatory liver disease, and its pathogenesis is not fully understood. Our previous study discovered that receptor interacting protein kinase 3 (RIP3) is correlated with serum transaminase l
Publikováno v:
International Journal of Biological Sciences. 18:2406-2418
A successful pregnancy requires the maternal immune system to tolerate an allogeneic fetus. The incidence of preeclampsia and other complications related to impaired fetal tolerance is lower during the second pregnancy than during the first pregnancy
Publikováno v:
International Journal of Biological Sciences
N6-methyladenosine (m6A) is the most prevalent chemical modification in eukaryotic messenger RNAs. By participating in various RNA-related bioprocesses including RNA decay, splicing, transport and translation, m6A serves as a pivotal regulator of RNA
Publikováno v:
International Journal of Biological Sciences. 18:2261-2276
Yap is required for ovarian follicle and early embryo development, but little information is available regarding its physiological significance in decidualization. Here we determine the effects of YAP on decidualization, mitochondrial function, cell
ZDHHC22-mediated mTOR palmitoylation restrains breast cancer growth and endocrine therapy resistance
Autor:
Jiefeng Huang, Jie Li, Jun Tang, Yushen Wu, Fengsheng Dai, Ziying Yi, Yan Wang, Yunhai Li, Yue Wu, Guosheng Ren, Tingxiu Xiang
Publikováno v:
International Journal of Biological Sciences. 18:2833-2850
Palmitoylation is essential for the classic hallmarks of cancers through regulating protein stability and protein-protein interactions. ZDHHC22, as a well-known member of palmitoyltrans-ferase family, its role has not been revealed in cancer. We foun
Autor:
Chong Zhou, Xi He, Chang Tong, Honghui Li, Caifeng Xie, Yudong Wu, Lieliang Wang, Xiaohua Yan, Daya Luo, Yunpeng Tang, Zhongman Cheng, Xiangyang Xiong
Publikováno v:
International Journal of Biological Sciences. 18:1363-1380
Cancer-associated adipocytes (CAAs), which are adipocytes transformed by cancer cells, are of great importance in promoting the progression of breast cancer. However, the underlying mechanisms involved in the crosstalk between cancer cells and adipoc
Autor:
Marc, Bracko, Uwe Karsten, Simon
Publikováno v:
International Journal of Biological Sciences. 18:1627-1650
Viruses have become a prominent issue in public health, politics and economics due to the Covid-19 pandemic. Yet they have still met little attention in educational research, although misconceptions concerning viruses may contribute to antibiotics mi
Autor:
Pei-Ling, Chi, Chin-Chang, Cheng, Cheng-Chung, Hung, Mei-Tzu, Wang, Hsien-Yueh, Liu, Meng-Wei, Ke, Min-Ci, Shen, Kun-Chang, Lin, Shu-Hung, Kuo, Pin-Pen, Hsieh, Shue-Ren, Wann, Wei-Chun, Huang
Publikováno v:
International Journal of Biological Sciences
Pulmonary arterial hypertension (PAH) is characterized by muscularized pulmonary blood vessels, leading to right heart hypertrophy and cardiac failure. However, state-of-the-art therapeutics fail to target the ongoing remodeling process. Here, this s