Zobrazeno 1 - 10
of 84
pro vyhledávání: ''
Autor:
Lai Ling Tsang, Gang Li, Fuyuan Yang, Ye Chun Ruan, Zhihui Weng, Jiawei Huang, Tobias D Merson, Zeyuan Ji, Jiacheng Lin, Xiaohua Jiang, Chao Wan, Kin Pong U
Publikováno v:
Theranostics
Aims: Hypoxic-ischaemic encephalopathy (HIE) is one of the most serious complications in neonates and infants. Mesenchymal stromal cell (MSC)-based therapy is emerging as a promising treatment avenue for HIE. However, despite its enormous potential,
Autor:
Qingwei Meng, Yongxu Zhou, Jianxiong Geng, Bo Pan, Lishuang Qi, Yan Yu, Yingyue Cao, Zijie Wang, Xin Wang, Zixin Wei, Shi Jin, Yaoguo Lang, Shanqi Xu
Publikováno v:
International Journal of Biological Sciences
RNA-binding motif protein 10 (RBM10), one of the members of the RNA-binding protein (RBP) family, has a tumor suppressor role in multiple cancers. However, the functional role of RBM10 in lung adenocarcinoma (LUAD) and the underlying molecular mechan
Autor:
Hong-Wen Deng, Yun Gong, Zun Wang, Li-Jun Tan, Yang Junxiao, Yiping Chen, Xiang Qiu, Cui Zhou, Liang Cheng, Jonathan Greenbaum, Siyuan Tang, Hong-Mei Xiao, Yusheng Li, Martin R. Schiller, Xiaohua Li, Yu Chen, Huixi Zhang, Yihe Hu, Hui Shen, Yang Xucheng, Ying Liu, Jie Xie
Publikováno v:
International Journal of Biological Sciences
Bone marrow-derived mesenchymal stem cells (BM-MSCs) are multipotent stromal cells that have a critical role in the maintenance of skeletal tissues such as bone, cartilage, and the fat in bone marrow. In addition to providing microenvironmental suppo
Autor:
Sung Eun Chang, Youngsup Song, Seunghyun Bang, Ha-Ri Lee, Min-Ah Kim, Ki-Hyun Kim, Young-Ho Kang, Woo-hyung Kim, Hanju Yoo
Publikováno v:
Theranostics
Background: Although CREB phosphorylation is known to be essential in UVB/cAMP-stimulated melanogenesis, CREB null mice did not show identifiable pigmentation phenotypes. Here, we show that CREB-regulated transcription co-activator 3 (CRTC3) quantita
Autor:
Zhenmin Wang, Zhizhong Li, Guozhi Xiao, Canling Long, Songlin Peng, Zhiteng Bao, He Xiaoqin, Chen Gaoyang, Wanze Tang, Xin Chen, Dazhi Yang, Tan Baoyu, William W. Lu, Shang Wang
Publikováno v:
International Journal of Biological Sciences
Bone remodeling is a dynamic process between bone formation mediated by osteoblasts and bone resorption mediated by osteoclasts. Disrupted bone remodeling is a key factor in postmenopausal osteoporosis, a metabolic disorder characterized by deteriora
Autor:
Tan Jun, Zi Dan, Li Song, Xie Feifei, Chen Jiang, Xing Zhao, Zhifeng Lei, Qinmin Tang, Ling Mo
Publikováno v:
International Journal of Biological Sciences
SARS-CoV-2 invades host cells mainly through the interaction of its spike-protein with host cell membrane ACE2. Various antibodies targeting S-protein have been developed to combat COVID-19 pandemic; however, the potential risk of antibody-dependent
Autor:
Sijia Wang, Xiaoyu Han, Yanjie Guo, Qiongqiong Jia, Boqun Liu, Yingpu Sun, Yang Yan, Lanlan Fang, Jung-Chien Cheng, Yiran Li
Publikováno v:
International Journal of Biological Sciences
Rationale: Growth differentiation factor-8 (GDF-8), also known as myostatin, belongs to the transforming growth factor-beta (TGF-β) superfamily. GDF-8 is expressed in the ovary and regulates various ovarian functions. Ovarian hyperstimulation syndro
Autor:
Xiaohua Douglas Zhang, Runpei Lin, Hui Wang, Haisheng Hu, Mingshan Xue, Ning Li, Yifeng Zeng, Yingjie Zhen, Luqian Zhou, Hao Chen, Zhifeng Huang, Teng Zhang, Baoqing Sun
Publikováno v:
International Journal of Biological Sciences
Dysregulated immune response and abnormal repairment could cause secondary pulmonary fibrosis of varying severity in COVID-19, especially for the elders. The Krebs Von den Lungen-6 (KL-6) as a sensitive marker reflects the degree of fibrosis and this
Autor:
Giuseppina Milano, Edoardo Lazzarini, Tudor Emanuel Fertig, Dario Di Silvestre, Lucio Barile, Fumihiro Sanada, Carolina Balbi, Yoshiaki Taniyama, Thomas F. Lüscher, Pierluigi Mauri, Giuseppe Vassalli, Sara Bolis, Mihaela Gherghiceanu
Publikováno v:
Theranostics
Although a small number of cardiomyocytes may reenter the cell cycle after injury, the adult mammalian heart is incapable of a robust cardiomyocyte proliferation. Periostin, a secreted extracellular matrix protein, has been implicated as a regulator
Autor:
Guanzhong Chen, Bowen Liu, Jiyan Chen, Hong Li, Chunyun Zhou, Jia Liu, Ziling Mai, Enzhao Chen, Liyao Zhang, Yulin Liao, Zhaodong Guo, Huanqiang Li, Min Li, Shiqun Chen, Shanyi Huang, Ning Tan, Li Lei, Guoli Sun, Yong Liu, Jin Liu
Publikováno v:
International Journal of Biological Sciences
Background: Post-contrast acute kidney injury (PC-AKI) is a severe complication of cardiac catheterization. Emerging evidence indicated that long non-coding RNAs (lncRNAs) could serve as biomarkers for various diseases. However, the lncRNA expression