Zobrazeno 1 - 10
of 35
pro vyhledávání: ''
Autor:
Qianghua Zhou, Jingtong Zhang, Ruihui Xie, Liang Cheng, Xu Chen, Shengmeng Peng, Yangjie Zhang, Haixia He, Tianxin Lin, Ming Huang, Sen Liu, Jian Huang
Publikováno v:
Theranostics
Purpose: Advanced prostate cancer (PCa) has limited treatment regimens and shows low response to chemotherapy and immunotherapy, leading to poor prognosis. Histone modification is a vital mechanism of gene expression and a promising therapy target. I
Autor:
Chen Chen, Weiwei Wang, Yuying Guo, Weitang Yuan, Zhenyu Ji, Luyang Zhao, Zhenqiang Sun, Guixian Wang, Xiuxiu Yang, Yaxin Guo, Qin Dang, Bo Shao, Jinbo Liu, Qiaozhen Kang, Shuaixi Yang, Quanbo Zhou
Publikováno v:
Theranostics
Tumor metastasis is the leading cause of death in patients with colorectal cancer (CRC). Circular RNAs (circRNAs) have been shown to be involved in cancer progression. However, the regulatory mechanisms of circRNAs involved in CRC tumor metastasis ar
Autor:
Yongzhan Nie, Limin Xia, Danfei Liu, Kaichun Wu, Mengyu Sun, Wenjie Huang, Dean Tian, Tongyue Zhang, Xiaoyu Ji, Daiming Fan, Weibo Feng, Jie Chen, Yijun Wang, Meng Xie, Chenyang Qiao
Publikováno v:
Theranostics
Background: Metastasis is the major reason for the high mortality of colorectal cancer (CRC). However, the molecular mechanism underlying CRC metastasis remains unclear. Here, we report a novel role of homeobox B5 (HOXB5), a member of the HOX family,
Autor:
Min Yang, Jianbao Zheng, Xiuqin Ma, Lina Qiao, Wei Wang, Jin Xianzhen, Xuejun Sun, Chunyan Liao, Hui Fan, Wei Zhao
Publikováno v:
International Journal of Medical Sciences
Long non-coding RNA musculin antisense RNA 1 (lncRNA MSC-AS1) has been recognized as an oncogene in pancreatic cancer, hepatocellular carcinoma, nasopharyngeal carcinoma, and renal cell carcinoma. However, the functional significance of MSC-AS1 and i
Autor:
Tianqi Zhang, Chen Li, Jianfang Li, Zhenggang Zhu, Zhenqiang Wang, Maneesh Kumarsing Beeharry
Publikováno v:
International Journal of Biological Sciences. 17:1629-1643
Long non-coding RNA (lncRNA) small nucleolar RNA host gene 12 (SNHG12) plays important roles in the pathogenesis and progression of cancers. However, the role of SNHG12 in the metastasis of gastric cancer (GC) has not yet been thoroughly investigated
Publikováno v:
International Journal of Medical Sciences
The incidence of cutaneous melanoma (CM) increased since the 1970s, and also along with an unfavorable prognosis. CM patients have been verified benefits from immunotherapy, and granzymes (GZMs) comprise more than 90% of the cytolytic granules secret
Autor:
Kenichi Mizutani, Shilei Zhao, Reimon Yamaguchi, Xin Guo, Hidetaka Uramoto, Chundong Gu, Sohsuke Yamada
Publikováno v:
International Journal of Medical Sciences
Background: Teashirt homolog 2 (TSHZ2) is essential for maintaining cellular homeostasis and regulating transcription on neoplasia development. However, the regulation of TSHZ2 in lung tumorigenesis and the underlying mechanisms remain unclear. Objec
Autor:
Xia Wang, Yu Zhang, Lanqi Gong, Liangzhan Sun, Yongxu Jia, Shayi Wu, Yanru Qin, Shuo Han, Dora L.W. Kwong, Ying Tang, Ying Wang, Xin Yuan Guan, Ngar-Woon Kam, Zhaojie Lyu
Publikováno v:
Theranostics
Objective: The transcription factor forkhead box protein O1 (FOXO1) is critical for regulating cytokine and chemokine secretion. However, its function in the tumor microenvironment (TME) remains largely unexplored. In this study, we characterized the
Publikováno v:
International Journal of Medical Sciences
Background: Platelets play important roles in tumorigenesis, angiogenesis and metastatic dissemination of tumor cells. Radiofrequency ablation (RFA) could increase the circulating tumor cells in patients with primary or metastatic lung tumors. Whethe
Autor:
Jian Yu, Chaoyuan Kuang, Lin Shen, Jingshan Tong, Haiping Pei, Lin Zhang, Xiangping Song, Shan Zeng, Robert E. Schoen
Publikováno v:
Theranostics
Intrinsic and acquired resistance to targeted therapies is a significant clinical problem in cancer. We previously showed that resistance to regorafenib, a multi-kinase inhibitor for treating colorectal cancer (CRC) patients, can be caused by mutatio