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Autor:
Yangang Wang, Zhongchao Wang, Shihua Zhao, Xiaoyi Liu, Yan Feng, Jianxia Hu, Jingwei Chi, Kui Che
Publikováno v:
Cancer Biomarkers. 21:883-891
BACKGROUND Epidemiological data have revealed that colorectal cancer (CRC) risk is increased in patients with Metabolic syndrome. OBJECTIVE To explore the expressions of IGF-1, ERK, GLUT4, IRS-1 in MS patients with CRC and their associations with the
Publikováno v:
Cancer Biomarkers. 21:925-934
Background Molecular target therapy has become a hot spot in cancer treatment, finding effective targets for diffuse large B cell lymphoma (DLBCL) is an urgent problem. Objective To detect the expression level of C-C motif chemokine ligand 18 (CCL18)
Publikováno v:
Cancer Biomarkers. 21:547-555
BACKGROUND High-mobility group A2 (HMGA2) has been investigated to be associated with tumorigenesis; however, the expression pattern and clinical significance of HMGA2 in non-small cell lung cancer (NSCLC) remains poorly understood. The purpose of th
Publikováno v:
Cancer Biomarkers. 21:261-267
BACKGROUND colorectal cancer (CRC) is the second leading cause of cancer and cancer-related death in the world. Noninvasive biomarkers for early diagnosis of CRC are highly demanded. OBJECTIVE The up-regulation of specific microRNAs (miRNAs) in serum
Autor:
Tianping Yu, Ni Chen, Qing Mao, Xiang Wang, Bing Kong, Yanhui Liu, Mingrong Zuo, Mao Li, Ruofei Liang
Publikováno v:
Cancer Biomarkers. 20:183-189
Background While major progress has been made in diagnosis and treatment of gliomas based on molecules, molecular features of thalamic glioma have rarely been reported till now. Objective IDH1 mutation is important for prognosis of gliomas and repres
Autor:
Jiao Zhou, Ling-Ling Zhai, Zhaoqun Deng, Jing Zhang, Jiang Lin, Xi Tang, Ling-Yu Zhou, Minse-Evola Deniz Vanessa, Jia-Yu Yin, Wen Peng
Publikováno v:
Cancer Biomarkers. 18:305-312
This study was intended to investigate the expression status of Vimentin 2p (VIM 2p), a pseudogene of Vimentin, and further analyze its clinical significance in AML patients.Real-time quantitative PCR (RQ-PCR) was employed to explore the expression s
Autor:
Abir H Alsaid, Ali M. Al-Amri, Rudaynah Al Ali, Yehia S. Mohamed, Cyril Cyrus, Tariq Mohammad Hashim, Shahanas Chathoth, Chittibabu Vatte, Amein Al Ali
Publikováno v:
Cancer Biomarkers. 16:377-383
BACKGROUND HNSCC is the sixth most common human cancer globally. In Saudi Arabia, HNSCC accounts for seven percent of all newly diagnosed cancer cases. The PIK3CA is one of the most commonly mutated oncogene in human malignancies, including HNSCC. OB
Autor:
Carsten Bokemeyer, Luigi Terracciano, Ronald Simon, Guido Sauter, Fritz Jaenicke, Uwe Heilenkötter, Annette Lebeau, Matthias Choschzick
Publikováno v:
Cancer Biomarkers. 8:53-60
MDM2 is overexpressed and amplified in a number of malignant tumors including breast carcinomas. Cell culture experiments showed a close connection between %of MDM2 expression and estrogen receptor status in breast cancer cell lines. Only little is k
Autor:
Udo Kronberg, Pilar Carvallo, Luis Contreras, Maki Kobayashi, Juan Carlos Triviño, Paulina Orellana, Cynthia Villarroel, Ana María Wielandt, Hiroshi Kawachi, Francisco López-Köstner, Karin Alvarez, Marjorie De la Fuente
Publikováno v:
Tumor Biology, Vol 39 (2017)
Colorectal cancer is a multistep process affecting several signaling pathways including EGFR (epidermal growth factor receptor), a therapeutic target for metastatic disease. Our aim was to characterize the mutational and expression profiles of the EG