Zobrazeno 1 - 10
of 50
pro vyhledávání: ''
Publikováno v:
Cancer Biomarkers. 21:179-186
PI3K/Akt/mTOR signaling pathway plays an important role in tumor development. mTOR overexpression and PI3K/ Akt/mTOR signaling pathway enhancement were found in endometrial cancer (EC). MiR-101 was found downregulated in EC. Bioinformatics analysis s
Autor:
G. Aravantinos, E. Vasilaki, Maria Tzouvala, Maria Gazouli, Hector Katifelis, Antonios Vezakis, D. Moschovis, G Karamanolis, Evangelia Legaki
Publikováno v:
Cancer Biomarkers. 24:117-123
BACKGROUND Long non-coding RNAs (lncRNAs) are emerging as candidate biomarkers of cancer, having regulatory functions in both oncogenic and tumor-suppressive pathways. Concerning pancreatic cancer (PC), deregulation of lncRNAs involved in tumor initi
Publikováno v:
Cancer Biomarkers. 23:505-513
OBJECTIVE The aim of this study was to evaluate the correlation of circular RNA itchy E3 ubiquitin protein ligase (Circ-ITCH) expression with clinicopathological features and survival in patients with epithelial ovarian cancer (EOC), and to explore i
Autor:
Rong Xie, Shuyong Zhang, Zhi Wang, Chengfeng Xiong, Meijun Zhong, Wanzhi Chen, Tao Zhou, Yunxia Lv, Jichun Yu
Publikováno v:
Cancer Biomarkers. 23:185-191
BACKGROUND Long non-coding RNAs (lncRNAs) were recently identified as crucial regulators of papillary thyroid cancer (PTC). However, the clinical role and regulatory functions of lncRNA cancer susceptibility candidate 2 (CASC2) in PTC remain unknown.
Publikováno v:
Cancer Biomarkers. 22:693-700
OBJECTIVE To analysis the expression of VEGF in gastric carcinoma cell and tumor tissue, our study determined the relationship between the expression of VEGF and tumor incidence, metastasis and prognosis in human gastric carcinoma. METHODS Treatment
Autor:
Meina Wu, Ziping Wang, Jun Zhao, Jia Zhong, Xue Yang, Yuyan Wang, Hanxiao Chen, Jing Huang, Minglei Zhuo, Tianzhuo Zhang, Tongtong An
Publikováno v:
Cancer Biomarkers. 22:467-476
BACKGROUND The PD-L1 antibody atezolizumab has shown promising efficacy in patients with advanced non-small cell lung cancer. But the predictive marker of clinical benefit has not been identified. OBJECTIVE This study aimed to search for potential pr
Publikováno v:
Cancer Biomarkers. 22:405-415
Neoadjuvant chemotherapy (NCT) is the standard treatment for locally advanced breast cancer (LABC). Pathological complete response (pCR) is commonly used as a valid predictor of NCT long-term outcomes. Blood-based tumor biomarkers have the potential
Publikováno v:
Cancer Biomarkers. 22:427-434
Backgrounds MicroRNAs (miRNAs) are some RNA molecules that negatively regulate gene expression by binding to the 3'-untranslated region (3'-UTR) of target mRNA molecules. The aim of the study is to investigate the clinical role and functional effects
Publikováno v:
Cancer Biomarkers. 22:301-310
Background Patients with small (⩽ 2 cm) invasive lung adenocarcinoma are at high risk of poor prognosis and disease recurrence after complete surgical resection. Therefore, identification of high-risk individuals from these patients emerges as an u
Publikováno v:
Cancer Biomarkers. 22:283-299
Background LncRNA and microRNA play an important role in the development of human cancers; they can act as a tumor suppressor gene or an oncogene. LncRNA GAS5, originating from the separation from tumor suppressor gene cDNA subtractive library, is co