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pro vyhledávání: '"Paul J. Galardy"'
Autor:
Steven C. Ziesmer, Sajjad Hussain, Paul J. Galardy, Stephen M. Ansell, Andrew L. Feldman, Chittaranjan Das
Publikováno v:
Molecular and Cellular Biology. 33:1188-1197
Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that regulates processes including mRNA translation, proliferation, and survival. By assembling with different cofactors, mTOR forms two complexes with distinct biological functions. R
Publikováno v:
Cell Cycle. 8:1688-1697
It is increasingly apparent that ubiquitin (Ub) mediated events are critical in cell proliferation. With much attention placed on the ubiquitin-proteasome pathway as a target for pharmacologic intervention, we must consider the role of deubiquitinati