Zobrazeno 1 - 2
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pro vyhledávání: '"Karin Jirström"'
Autor:
Karolina Edlund, Karin Jirström, Patrick Micke, Roger Henriksson, Johan Botling, Samuel Kvarnbrink, Mikael Johansson, Håkan Hedman, David Lindquist, Terese Karlsson
Publikováno v:
Acta Oncologica. 54:1113-1119
Background. The leucine-rich repeats and immunoglobulin-like domains (LRIG) family of transmembrane proteins are involved in the regulation of cellular signal transduction. LRIG1 is an endogenous inhibitor of receptor tyrosine kinases (RTKs) and an e
Publikováno v:
Cell Cycle. 10:956-962
The retinoblastoma tumor suppressor (RB) is important for retaining cell cycle control and loss of RB function is commonly observed in various malignancies. Experimental and animal studies have shown that RB knockdown in ER+ (estrogen receptor) cell