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pro vyhledávání: '"Joseph Bass"'
Publikováno v:
Cellular Logistics. 1:32-36
The molecular clock controls 24-hour cycles of behavioral and physiological processes across the day-night cycle. Disruption of circadian rhythmicity has been implicated in the pathogenesis of several diseases, including the metabolic syndrome, altho
Autor:
Mei Ling Chen, William S. Chen, Louis H. Philipson, Joseph Bass, Nissim Hay, Yongmei Luo, Kevin Coleman, Yong Wang, Pei Zhang Xu, Wanda M. Haschek, Xiao Ding Peng, Sang-Min Jeon
Publikováno v:
Molecular and Cellular Biology. 29:3151-3162
Phenotypic analyses of mice null for the individual Akt isoforms suggested that they are functionally distinct and that only Akt2 plays a role in diabetes. We show here that Akt isoforms play compensatory and complementary roles in glucose homeostasi