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pro vyhledávání: '"Gerald J Obermair"'
Stabilization of negative activation voltages of Cav1.3 L-Type Ca2+-channels by alternative splicing
Autor:
Alexandra Pinggera, Jörg Striessnig, Petronel Tuluc, Nadja T. Hofer, Yuliia V. Nikonishyna, Gerald J. Obermair, Eva Maria Fritz
Publikováno v:
Channels
article-version (VoR) Version of Record
article-version (VoR) Version of Record
>Low voltage-activated Cav1.3 L-type Ca2+-channels are key regulators of neuronal excitability controlling neuronal development and different types of learning and memory. Their physiological functions are enabled by their negative activation voltage
Autor:
Gerald J. Obermair, Alexandra Koschak, Silja B Horak, Martina J. Sinnegger-Brauns, Claudia Wild, Katrin Schulze, Robert Tampé, Jörg Striessnig, Katrin Watschinger
Publikováno v:
Channels. 2:461-473
Depolarisation-induced Ca2+ influx into electrically excitable cells is determined by the density of voltage-gated Ca2+ channels at the cell surface. Surface expression is modulated by physiological stimuli as well as by drugs and can be altered unde