Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Andres J. Klein-Szanto"'
Autor:
Olena Barbash, Anil K. Rustgi, Mariusz A. Wasik, Andres J. Klein-Szanto, Laura Pontano Vaites, Darshan Roy, J A Diehl, Zhaorui Lian, Eric K. Lee
Publikováno v:
Molecular and Cellular Biology. 31:4513-4523
Skp1-Cul1-F-box (SCF) E3 ubiquitin ligase complexes modulate the accumulation of key cell cycle regulatory proteins. Following the G(1)/S transition, SCF(Fbx4) targets cyclin D1 for proteasomal degradation, a critical event necessary for DNA replicat
Autor:
Munenori Takaoka, Carmen Z. Michaylira, Andres J. Klein-Szanto, Hiroshi Nakagawa, Claudia D. Andl, Douglas B. Stairs, Ben Rhoades, Seok-Hyun Kim, Wafik S. El-Deiry, Takaomi Okawa, Cameron N. Johnstone, James J. Lee
Publikováno v:
Cancer Biology & Therapy. 6:534-540
Insulin-like growth factor binding protein (IGFBP)-3 exerts either proapoptotic or growth stimulatory effects depending upon the cellular context. IGFBP-3 is overexpressed frequently in esophageal cancer. Yet, the role of IGFBP-3 in esophageal tumor