Zobrazeno 1 - 10
of 7 139
pro vyhledávání: ''
Autor:
Philippe Korn, Simon Spalthoff, M. Zerfowski, Ulf T. Eysel, Nils-Claudius Gellrich, Philipp Jehn
Publikováno v:
Current Eye Research. 47:461-467
PURPOSE OF THE STUDY Traumatic optic neuropathy (TON) is a rare but serious consequence of head injuries. The optimal therapy for TON remains controversial, and standardized recommendations are lacking. The most common therapies used are steroid admi
Autor:
Jasna Pesic, Vladimir Vidovic, Ivana Kolarov Bjelobrk, Jasna Trifunovic, Nemanja Petrovic, Jelena Radic, Bojana Vranjkovic, Bojana Andrejic Visnjic
Publikováno v:
Journal of Chemotherapy. 34:264-271
The choice of the anti-HER2 agent depends on country-specific availability, the specific, previously administered anti-HER2 therapy and the relapse-free interval, although there is not much published data on the use of lapatinib after progression on
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 9356-9366 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 9356-9366 (2021)
Diabetes mellitus is an important public health problem worldwide. Insulin deficiency caused by pancreatic β cell dysfunction is an important pathogenic factor of diabetes mellitus. This study evaluated whether empagliflozin (EMPA) protects the panc
Autor:
David A. Russler-Germain, Ramzi Abboud, Thomas J Fountaine, Eric Huselton, Jeffrey R. Andolina, Luke Eastburg, John F. DiPersio
Publikováno v:
Leukemia & Lymphoma. 63:222-226
Due to the evolving use of haploidentical donor grafts in hematopoietic cell transplantation, there is increased need to better understand the risks and benefits of using bone marrow versus peripheral blood grafts, as well as how specific pre-transpl
Autor:
L. Pivackova, Jan Klimas, Zuzana Kmecova, Eva Velasova, Peter Krenek, E. Malikova, Simona Trubacova, Peter Balis, Gabriel Doka
Publikováno v:
Clinical and Experimental Hypertension. 44:101-112
Background Caveolin-1 (cav-1) plays a role in pulmonary arterial hypertension (PAH). Monocrotaline (MCT)-induced PAH is characterized by a loss of cav-1 in pulmonary arteries; however, less is known regarding its role in the hypertrophied right ventr
Autor:
Elena Samochatova, Alexander Popov, Svetlana Plyasunova, Alexey Maschan, Vladimir Zhogov, Natalia Miakova, Liudmila Potapenko, Alexandra Semchenkova, Anastassia Rudneva
Publikováno v:
Leukemia & Lymphoma. 63:217-221
Publikováno v:
Cancer Management and Research
Platelet-derived growth factor-beta (PDGFRB) gene maps for the receptor tyrosine kinase PDGRFβ. PDGFRB gene fusions have been implicated in multiple myeloid and lymphoid neoplasms and have shown exquisite sensitivity to tyrosine kinase inhibitors. W
Autor:
Ying Han, Xingxing Wang, Xuanxuan Liu, Li Zhao, Shuo Sun, Haiyang Tang, Changlei Bao, Ang Luo, Yan Pan
Publikováno v:
Drug Design, Development and Therapy
Purpose Endothelial dysfunction and the subsequent decrease in endothelium-dependent vascular relaxation of small arteries are major features of hypertension. Artemisinin, a well-known antimalarial drug, has been shown to exert protecting roles again
Autor:
Yue Guo, Zhao-Hui Mo, Bo Fan, Xian-Ping Wu, Bennett K. Ng, Ying-Hui Zhou, Min Wang, Chen-Yi Tang, John A. Shepherd, Hou-De Zhou
Publikováno v:
International Journal of General Medicine
Yue Guo,1,2,* Ying-Hui Zhou,1,* Xian-Ping Wu,1 Chen-Yi Tang,1 Min Wang,3 Zhao-Hui Mo,4 John A Shepherd,5 Bennett K Ng,5 Bo Fan,5 Hou-De Zhou1 1National Clinical Research Center for Metabolic Diseases, Hunan Provincial Key Laboratory of Metabo
Autor:
Yuki Kato, Masahiro Seike, Akihiko Miyanaga, Yasuhiro Kato, Takahiro Suzuki, Kaoru Kubota, Yasuhiro Terasaki, Masaru Matsumoto, Yuji Minegishi, Akihiko Gemma, Shinji Nakamichi, Rintaro Noro
Publikováno v:
OncoTargets and therapy
Antibody–drug conjugate (ADC) was novel type of anticancer drugs. Trastuzumab deruxtecan (T-DXd), a human epidermal growth factor receptor 2 (HER2) targeting ADC, can be a novel treatment option for HER2 alternation (mutation, expression, amplifica