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Autor:
Chen, Guo, Qin, Xiaoping, Wang, Yu, Gao, Biyun, Ling, Muan, Yin, Wenjun, Li, Yutong, Pan, Bin
Publikováno v:
Cell Cycle
LncRNAs involve in the autophagy to regulate prostate cancer (PCA) initiation and progression. Therefore, it urges to explore more significant AR-lncRNAs in PCa. mRNA data and clinical information of PCa were achieved from TCGA database, and ARGs wer
Pannexin1 inhibits autophagy of cisplatin-resistant testicular cancer cells by mediating ATP release
Publikováno v:
Cell Cycle
Pannexin1 (Panx-1) is a gap junction channel protein that mediates the release of intracellular ATP during autophagy, and thus plays an important role in tumor cell apoptosis and chemo-resistance. However, the role of Panx-1 in cisplatin-resistance o
Autor:
Joel, Rosenbloom
Publikováno v:
Connective Tissue Research. 63:200-209
This biography of Dr. Joel Rosenbloom is published on the occasion of the 50th anniversary of the journal. Dr. Rosenbloom presents the scientific milestones and achievements throughout his career emphasizing events that have spurred him to launch int
Autor:
Luke J Nelson, Kyleen E Castro, Binzhi Xu, Junyi Li, Nguyen B Dinh, Jordan M Thompson, Jordan Woytash, Kevin R Kipp, Olga V Razorenova
Publikováno v:
Cell cycle (Georgetown, Tex.), vol 21, iss 10
Clear cell renal cell carcinoma (CC-RCC) remains one of the most deadly forms of kidney cancer despite recent advancements in targeted therapeutics, including tyrosine kinase and immune checkpoint inhibitors. Unfortunately, these therapies have not b
Publikováno v:
Bioengineered. 13:5598-5612
N6-Methyladenosine (m6A) is the most abundant modifications in human messenger RNAs (mRNAs). This study aimed at investigating the function and mechanism of demethyltransferase fat mass and obesity-associated protein (FTO) in prostate cancer(PCa). Th
Autor:
Saad Aldalaqan, Caroline Dalgliesh, Sara Luzzi, Chileleko Siachisumo, Louise N Reynard, Ingrid Ehrmann, David J. Elliott
Publikováno v:
Cell Cycle. 21:219-227
High levels of transcription and alternative splicing are recognized hallmarks of gene expression in the testis and largely driven by cells in meiosis. Because of this, the male meiosis stage of the cell cycle is often viewed as having a relatively p
Autor:
Sven F. Garbade, Darius Ebrahimi-Fakhari, Markus Ries, Stefan Kölker, Steffen Syrbe, Georg F. Hoffmann, Afshin Saffari, Julian E. Alecu, Julian Schröter
Publikováno v:
Autophagy
WDR45-related neurodevelopmental disorder (NDD) is a clinically-heterogenous congenital disorder of macroautophagy/autophagy. The natural history of this ultra-orphan disease remains incompletely understood, leading to delays in diagnosis and lack of
Autor:
David Gosset, Loris Roncali, Yoan Laurent, Chantal Pichon, Flora Reverchon, Emmanuel Garcion, Patrick Baril, Audrey Rousseau, Francisco Martin, Patrick Midoux, Claire Loussouarn, Viorel Simion
Publikováno v:
RNA Biology/RNA Biol.
RNA Biology/RNA Biol., Georgetown, TX : Landes Bioscience (2015-: Philadelphia, PA : Taylor & Francis), 2021, Online ahead of print. ⟨10.1080/15476286.2021.1978202⟩
RNA Biol
RNA Biology/RNA Biol., 2021, Online ahead of print. ⟨10.1080/15476286.2021.1978202⟩
RNA Biology/RNA Biol., Georgetown, TX : Landes Bioscience (2015-: Philadelphia, PA : Taylor & Francis), 2021, Online ahead of print. ⟨10.1080/15476286.2021.1978202⟩
RNA Biol
RNA Biology/RNA Biol., 2021, Online ahead of print. ⟨10.1080/15476286.2021.1978202⟩
International audience; A major unresolved challenge in miRNA biology is the capacity to monitor the spatiotemporal activity of miRNAs expressed in animal disease models. We recently reported that the miRNA-ON monitoring system called RILES (RNAi-ind
Publikováno v:
Cell Cycle
Laryngeal squamous cell cancer (LSCC) is one of the most common malignant tumors in head and neck tumors. Our previous study has revealed that hsa_circ_0006232 is abnormally expressed in LSCC. This study attempts to verify the biological role of hsa_
Autor:
Shikun Yang, Aimei Li, Qin Liao, Hao Zhang, Li Zheng, Hailong Han, Jianwen Wang, Bin Yi, Zhaoxin Hu
Publikováno v:
Autophagy. 18:877-890
Diabetic nephropathy (DN) has become a major cause of end-stage renal disease, and autophagy disorder is implicated in the pathogenesis of DN. Our previous studies found that vitamin D (VD) and VDR (vitamin D receptor) played a renoprotective role by