Zobrazeno 1 - 10
of 2 197
pro vyhledávání: ''
Autor:
Chao Chen, Jing Gao, Dan Chen, Jinyu Liu, Biwei He, Yan Chen, Huijuan Zhang, Xingyu Yang, Weiwei Cheng
Publikováno v:
Cell Cycle. 21:2517-2532
Preeclampsia (PE) is a pregnancy-associated disease that may cause maternal and fetal morbidity and mortality. The dysregulation of microRNAs (miRNAs) and their potential functions has been an important direction for elucidating the mechanism of pree
Autor:
Luke J Nelson, Kyleen E Castro, Binzhi Xu, Junyi Li, Nguyen B Dinh, Jordan M Thompson, Jordan Woytash, Kevin R Kipp, Olga V Razorenova
Publikováno v:
Cell cycle (Georgetown, Tex.), vol 21, iss 10
Clear cell renal cell carcinoma (CC-RCC) remains one of the most deadly forms of kidney cancer despite recent advancements in targeted therapeutics, including tyrosine kinase and immune checkpoint inhibitors. Unfortunately, these therapies have not b
Autor:
Toru Suzuki, Miyuki Hoshina, Saori Nishijima, Naosuke Hoshina, Chisato Kikuguchi, Takumi Tomohiro, Akira Fukao, Toshinobu Fujiwara, Tadashi Yamamoto
Publikováno v:
RNA Biology
article-version (VoR) Version of Record
article-version (VoR) Version of Record
CCR4-NOT complex-mediated mRNA deadenylation serves critical functions in multiple biological processes, yet how this activity is regulated is not fully understood. Here, we show that osmotic stress induces MAPKAPK-2 (MK2)-mediated phosphorylation of
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 9561-9574 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 9561-9574 (2021)
Preeclampsia (PE), a pregnancy-specific syndrome, is the primary cause of maternal mortality. This work was designed to investigate the specific functions of PTPRO/ ERp44 in the biological behaviors of trophoblast cells and elucidate the underlying m
Autor:
Dadong Guo, Xiu-Zhen Lu, Qiuxin Wu, Jike Song, Dongmei Liu, Hongsheng Bi, Hui Wang, Zhongen Li
Publikováno v:
Cutaneous and Ocular Toxicology. 40:187-197
Oxidative stress has been recognised as an important mediator of apoptosis in lens epithelial cells. It also plays an important role in the pathogenesis of cataracts. It is reported that (-)-Epigallocatechin gallate (EGCG), the most abundant componen
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 85:1686-1696
To investigate the role of platelet-rich plasma (PRP) from different sources in alleviating oxidative stress and ameliorating melanogenesis in UVB-irradiated PIG1 cells, PIG1 cells were irradiated with 80 mJ/cm2 UVB prior to 1% PRP application and th
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 85:1818-1829
The effects of PADI4 and GAA on the senescence of Alzheimer's cells were explored in the present work. HT22 cells were treated with Aβ25-35 to establish an Alzheimer's model and were then treated with different concentrations of GAA and transfected
Publikováno v:
Cutaneous and Ocular Toxicology. 40:103-114
The main characteristic of proliferative vitreoretinopathy (PVR) is migration, adhesion, and epithelial-mesenchymal transition (EMT) of retinal pigment epithelial cells (RPE). Eupatilin is a naturally occurring flavone that has the potential to inhib
Autor:
Jian Wu, Pengfei Li, Huaijin Guan, Yu Cao, Xiaojuan Chen, Guowei Zhang, Lihua Kang, Yong Wang, Ying Wang, Tianqiu Zhou
Publikováno v:
Current Eye Research. 46:1353-1362
Purpose DNA damage contributes to the pathogenesis of age-related cataract (ARC) and is repaired through the nucleotide excision repair (NER) pathway, which includes ERCC6. Evidence has demonstrated that defective autophagy leads to lens organelle de
Publikováno v:
Cell Cycle
Liver fibrosis is a critical health issue in the world due to its rapidly increasing prevalence. It is of great demand to develop effective drugs for the treatment of liver fibrosis. 5-methoxytryptophan (5-MTP) has been reported to play an important