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Autor:
Gan Lin, Zhongning Lin, Shengwei Jiang, Liyin Zhang, Yun Zeng, Yuchun Lin, Chengyong He, Deng-Lin Zhan, Yankai Xia, Gang Liu, Huan Yao, Chuanli Yang
Publikováno v:
Nanotoxicology. 12:1198-1214
Ultra-small superparamagnetic iron oxide nanoparticles (USPIO-NPs) are widely used as clinical magnetic resonance imaging contrast agents for hepatic diseases diagnosis. USPIO-NPs often damage the hepatocytes and affect the function of liver but its
Publikováno v:
The Journal of Maternal-Fetal & Neonatal Medicine. 33:1125-1133
Introduction: The sufficient invasion and migration of human extravillous trophoblast (EVTs) cells are crucial for placentation. Inadequate invasion of trophoblasts may correlate with the development of preeclampsia. Many studies have suggested that
Publikováno v:
International Journal of Nanomedicine
Yueyang Lai,1,* Xuebo Xu,1,* Zhenyu Zhu,1 Zichun Hua1,21The State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China; 2Changzhou High-Tech Research Institute of Nanjing University and J
Autor:
Cleidiane de Sousa Rocha, Luís G. Dias, Tayana Mazin Tsubone, Paulo Siani, Isabel O. L. Bacellar, Aline B. de P. Abrantes, Adriana Yamaguti Matsukuma, Mauricio S. Baptista, Waleska Kerllen Martins, Ana Cláudia Viotto, Nayra Fernandes Santos
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Cells challenged by photosensitized oxidations face strong redox stresses and rely on autophagy to either survive or die. However, the use of macroautophagy/autophagy to improve the efficiency of photosensitizers, in terms of inducing cell death, rem
Autor:
Jean-Daniel Fauny, Diane Murera, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Frédéric Gros, Florent Arbogast, Johan Arnold, Sylviane Muller, Justine Weishaar
Publikováno v:
Autophagy
Autophagy, Taylor & Francis, 2019, 15 (2), pp.280-294. ⟨10.1080/15548627.2018.1516327⟩
Autophagy, Taylor & Francis, 2019, 15 (2), pp.280-294. ⟨10.1080/15548627.2018.1516327⟩
The involvement of macroautophagy/autophagy proteins in B-cell receptor (BCR) trafficking, although suspected, is not well understood. We show that ATG5 (autophagy related 5) contributes to BCR polarization after stimulation and internalization into
Publikováno v:
Autophagy
Endonuclease G (ENDOG), a mitochondrial nuclease, is known to participate in many cellular processes, including apoptosis and paternal mitochondrial elimination, while its role in autophagy remains unclear. Here, we report that ENDOG released from mi
Autor:
Ningyan Zhang, Kai Sun, Zening Wang, Chuan Chen, Mikhail G. Kolonin, Zhiqiang An, Li Yang, Xin Li, Xin Ge, Hyun Ho Lee, Yueshui Zhao, Philipp E. Scherer
Publikováno v:
Mol Cell Biol
Fibrosis is recognized as the major pathological change in adipose tissue during the development of obesity. However, the detailed mechanisms governing the interactions between the fibrotic components and their modifiers remain largely unclear. Here,
Autor:
Gustafson, Eric A., Seymour, Kimberly A., Sigrist, Kirsten, Rooij, Dirk G. D. E., Freiman, Richard N., Developmental Biology, Sub Developmental Biology
Publikováno v:
Molecular and Cellular Biology, 40(7). American Society for Microbiology
Molecular and cellular biology, 94(7):e00228-19. American Society for Microbiology
Mol Cell Biol
Molecular and cellular biology, 94(7):e00228-19. American Society for Microbiology
Mol Cell Biol
TAF4b is a subunit of the TFIID complex that is highly expressed in the ovary and testis and required for mouse fertility. TAF4b-deficient male mice undergo a complex series of developmental defects that result in the inability to maintain long-term
Autor:
Zhiwei Guo, Lijie Li, Wangqin Shu, Ruijie Gong, Yuanyuan Yang, Yuqi Li, Ziyu Wang, Zhiqi Xiong, Minjing He, Bo Gao
Publikováno v:
Mol Cell Biol
Chronic hepatitis B (CHB) remains a global health problem, carrying a high risk for progression into cirrhosis and liver failure. Molecular chaperones are involved in diverse pathophysiological processes including viral infection. However, the role o
Publikováno v:
Molecular and Cellular Biology
Through its ability to bind the ends of poly(ADP-ribose) (PAR) chains, the function of the histone variant macroH2A1.1, including its ability to regulate transcription, is coupled to PAR polymerases (PARPs). PARP1 also has a major role in DNA damage