Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ball, A."'
Autor:
Sheila L. Flack, Linda G. T. Gaines, Louise M. Ball, Jennifer M. Thomasen, Leena A. Nylander-French, Stephen G. Whittaker, Kenneth W. Fent
Publikováno v:
Biomarkers. 16:261-270
We investigated the utility of 1,6-hexamethylene diamine (HDA) hemoglobin adducts as biomarkers of exposure to 1,6-hexamethylene diisocyanate (HDI) monomer. Blood samples from 15 spray painters applying HDI-containing paint were analyzed for hemoglob
Publikováno v:
DNA Sequence. 19:326-331
Interferon regulatory factor-1 (IRF-1) plays important roles in host immunity, cell proliferation and apoptosis. The current GenBank sequence for human IRF-1 (accession number: L05072) was derived from a human placenta DNA library and reported in 199
Publikováno v:
Biomarkers. 10:127-137
Propylene oxide (PO) is an important industrial compound and a directly acting mutagen. Human exposure to PO can be monitored by the determination of haemoglobin adducts. An immunoassay that quantifies the N-terminal adduct N-(2-hydroxypropyl)valine
Publikováno v:
Biomarkers. 9:407-417
Ethylene oxide (EO) is an important industrial compound and a directly acting mutagen. Human exposure to it can be monitored by the determination of haemoglobin (Hb) adducts. An immunoassay that quantifies the N-terminal adduct N-(2-hydroxyethyl)vali
Autor:
JoAnn Scatina, S.E. Ball, B.G. Lake, John Kao, R.J. Price, Jinmei Pan, A.B. Renwick, Q. Xiang
Publikováno v:
Xenobiotica. 32:739-747
1. The aim was to employ real-time quantitative reverse transcription-polymerase chain reaction (RT-PCR) technology (TaqMan to examine the induction of some selected cytochrome P450 (CYP) forms in precision-cut rat liver slices. 2. Taqman primers and
Publikováno v:
Xenobiotica. 32:835-847
1. The metabolism of Zaleplon (CL-284,846; ZAL) has been studied in precision-cut human liver slices and liver cytosol preparations. 2. Human liver slices metabolized ZAL to a number of products including 5-oxo-ZAL (M2), N-desethyl-5-oxo-ZAL (M1) and
Autor:
Stuart Ball, David Loakes, Daniel M. Brown, Philip Steven Robinson, Michael Alan Reeve, Fergal Hill
Publikováno v:
Nucleosides and Nucleotides. 18:2685-2695
Recently we reported the use of octamer primers tailed with 5-nitroindole for use as primers in cycle sequencing reactions. Here we report the successful use of some other universal base analogues to improve the effectiveness of an octamer sequencing
Autor:
Monica A. Valentovic, Ball Jg
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 55:225-240
This study examined differences in toxicity between 2- and 4-aminophenol using a renal cortical slice model. Renal cortical slice toxicity for 2- and 4-aminophenol was also monitored in tissue from Sprague-Dawley and Fischer 344 (F344) rats in order
Publikováno v:
Xenobiotica. 28:361-371
1. In this study we have compared freshly cut and cultured precision-cut rat liver slices produced by the Krumdieck and Brendel-Vitron tissue slicers. 2. No significant differences were observed in levels of protein, potassium, total glutathione (i.e
Autor:
J. M. Tredger, Roger J. Price, Brian G. Lake, J.A. Beamand, S.E. Ball, A.B. Renwick, John Kao
Publikováno v:
Xenobiotica. 27:1165-1173
1. The effect of rifampicin on cytochrome P450 isoforms in the CYP1A and CYP3A subfamilies has been studied in 72-h cultured precision-cut human liver slices. 2. In cultured human liver slices 50 microM rifampicin induced testosterone 6 beta-hydroxyl