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Autor:
Babak PeyroShabany, Mansoureh Dehghani, Seyed Alireza Javadinia, Danial Fazilat-Panah, Pejman Porouhan, Farbod Hatami, James S Welsh, Maryam Nabavifard, Mona Ariamanesh, Mohammad Fereidouni
Publikováno v:
Cancer Investigation
article-version (VoR) Version of Record
article-version (VoR) Version of Record
ObjectivePatients with malignancy suffer from a compromised immune system due to either the effects of malignancies or treatments. Cancer patients are at higher risk of different infections particularly SARS-CoV2 and usually produce weaker response t
Autor:
Wenlan Chen, Yadan Wang, Yu Hu, Xiaoping Zhang, Heng Mei, Yaogong Wu, Qiuzhe Wei, Wenjing Li, Miaomiao Zhao
Publikováno v:
Leukemia & Lymphoma
Patients with hematological malignancies with immunodeficiency are at high risk for SARS-CoV-2 infection. We retrospective summarized clinical characteristics of coronavirus disease 2019 (COVID-19) inpatients with hematological malignancies, shared t
Autor:
Qi Chen, Hui Cheng, Jing Ding, Aijie Huang, Weiping Zhang, Gusheng Tang, Jianmin Wang, Shenglan Gong, Jianmin Yang, Xiaoxia Hu, Chongmei Huang, Min Liu
Publikováno v:
Leukemia & Lymphoma. 59:1073-1083
We investigated the impact of minimal residual disease (MRD) obtained from different approaches on the outcomes of 141 B lymphoblastic leukemia (B-ALL) patients. Among 169 samples with more than 5% blasts by morphology, 3.6% (6/169) were Flow-MRD neg
Autor:
Takashi Toya, Koji Iwato, Yoshiko Atsuta, Hiroyasu Ogawa, Toru Sakura, Jun Aoki, Tatsuo Ichinohe, Shuichi Ota, Shingo Yano, Saiko Kurosawa, Kaito Harada, Shohei Mizuno, Heiwa Kanamori, Naoyuki Uchida, Hideho Henzan, Yukiyasu Ozawa, Takahiro Fukuda, Masamitsu Yanada, Jinichi Mori
Publikováno v:
Leukemia & Lymphoma. 59:601-609
This study aimed at determining how cytogenetic risk status affects outcomes for patients with acute myeloid leukemia (AML) after undergoing various types of allogeneic hematopoietic cell transplantation (HCT). Of 7812 patients eligible for analysis,
Autor:
Jiali Huo, Yizhou Zheng, Shihong Lu, Min Wang, Jun Shi, Yahong You, Jinbo Huang, Neng Nie, Yingqi Shao, Zhendong Huang, Xingxin Li, Meili Ge, Jing Zhang
Publikováno v:
Leukemia & Lymphoma. 59:950-957
Acquired bone marrow failure syndromes (aBMFS) encompass a wide range of diseases. A study to investigate WT1 expression in BM was conducted in 387 patients with aBMFS in China. The WT1 level in patients with aplastic anemia (AA) was significantly lo
Autor:
Cristine Allmer, Tait D. Shanafelt, Carrie A. Thompson, James R. Cerhan, Matthew J. Maurer, Alexis D. Leal, Brian K. Link
Publikováno v:
Leukemia & Lymphoma. 59:695-701
Background Performance status (PS) is a measurement of a patient’s functional capabilities and has been validated as a prognostic indicator in patients with cancer. This study was conducted to compare patient and physician-rated Eastern Cooperative
Autor:
Katsuyoshi Takata, Hiaki Sato, Kana Washio, Lamia Abdalkader, Tadashi Yoshino, Hirokazu Tsukahara, Norio Shimizu, Yoshitoyo Kagami, Michiko Muraoka, Takashi Oka, Kazunori Nishizaki, Seiichi Kato, Hiroshi Kimura, Megumi Oda, Akira Shimada
Publikováno v:
Leukemia & Lymphoma. 58:2683-2694
The human herpes virus, Epstein-Barr virus (EBV), is a known oncogenic virus and plays important roles in life-threatening T/NK-cell lymphoproliferative disorders (T/NK-cell LPD) such as hypersensitivity to mosquito bite (HMB), chronic active EBV inf
Publikováno v:
Endocrine Research. :1-10
Glucagon-like peptide-1 (GLP-1) receptor agonists are a kind of very popular antidiabetes drugs. They promote cell proliferation and survival through activation of signaling pathways in human islet cells involving phosphate idylinositol 3 kinase (PI3
Publikováno v:
Leukemia & Lymphoma. 57:2351-2358
The susceptibility to Epstein-Barr virus (EBV)-related post-transplant lymphoproliferative disorder (PTLD) may be affected by the human leukocyte antigen (HLA) type. We investigated HLA-A and HLA-B allele frequencies, focusing on HLA-A1 and -A2, in a
Autor:
Shuya Chen, Zhen Zhou, Yaming Zhang, Ping Liu, Nana Zhe, Xiaojing Lin, Meisheng Yu, Jishi Wang, Bingqing Cheng
Publikováno v:
Cancer Biology & Therapy. 17:625-634
The bone marrow microenvironment plays an important role in the development and progression of AML. Leukemia stem cells are in a hypoxic condition, which induces the expression of HIF-1α. Aberrant activation of HIF-1α is implicated in the poor prog