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Publikováno v:
Journal of Drug Targeting. 29:1004-1015
Breast cancer (BC) remains a public health dilemma in the world and it is one of the leading causes of death among women. Trastuzumab is a kind of commonly-used drugs in the treatment of BC, which especially can provide substantial benefits for HER2-
Autor:
Francine M. Foss, Suzanne Xu
Publikováno v:
Expert Review of Anticancer Therapy. 21:1017-1028
The most common types of CTCL are mycosis fungoides (MF) and Sézary syndrome (SS). In both MF and SS, complete responses to treatment are uncommon. Recent developments and understanding of the biology of MF/SS have led to novel agents which may offe
Publikováno v:
Expert Opinion on Pharmacotherapy. 22:2105-2111
Introduction: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce blood glucose and glycosylated haemoglobin (HbA1c), the risk of hospitalization for heart failure (HF) and the incidence of serious adverse kidney function events (chronic kidney
Publikováno v:
Cancer Investigation. 39:597-606
Fourty-five breast cancer patients and 50 apparently healthy sex-matched controls from the University of Ilorin Teaching Hospital were enrolled in this study. Plasma D-dimer and fibrinogen were found to be significantly higher than controls; APTT was
Autor:
Albaraa Mohammed N. Marran, Sonia Radice, Emilio Clementi, Vera Battini, Robbert P. van Manen, Faizan Mazhar, Marco Pozzi, Michele Gringeri, Giulia Mosini, Carla Carnovale, Shahzad Akram
Publikováno v:
Expert Opinion on Biological Therapy. 21:1281-1290
Background: Studies in patients with immune-mediated inflammatory diseases (IMIDs) have inconsistently suggested that anti-TNFα therapy may be associated with excessive weight gain. Research design and methods: We performed a nested case/non-case an
Publikováno v:
Expert Review of Hematology. 14:621-632
Introduction: Waldenstrom's macroglobulinemia (WM) is a rare lymphoma characterized by the accumulation of IgM-secreting lymphoplasmacytic cells in the bone marrow and other organs. Clinical sequelae relate to direct tissue infiltration by malignant
Publikováno v:
Expert Opinion on Pharmacotherapy. 22:2199-2220
Given the relationship between the pathogenesis of obesity and type 2 diabetes mellitus (T2DM) as well as their significant health consequences, treatment strategies that can induce weight loss while achieving glycemic control are needed. Novel weigh
Publikováno v:
Acta Clinica Belgica. 77:721-725
OBJECTIVES To present a case of metastatic struma ovarii, to review the literature on malignant struma ovarii and to discuss the management in locoregional and metastatic disease. METHODS We present a case of an 82-year-old patient with a malignant s
Publikováno v:
Leuk Lymphoma
Uric acid drives acute kidney injury in tumor lysis syndrome (TLS). This study investigated the relationship between uric acid and changes in estimated glomerular filtration rate (eGFR) in adults at risk for TLS. Linear regression was used to evaluat
Autor:
Mika Mizoguchi, Michihisa Shiro, Nami Ota, Tomoko Noguchi, Kazuhiko Ino, Sawako Minami, Shigetaka Yagi, Yasushi Mabuchi, Sakiko Nanjo
Publikováno v:
Journal of Obstetrics and Gynaecology. 42:501-504
Retained products of conception (RPOC) is a complication that occurs in the second trimester of pregnancy. We enrolled 98 women who had a miscarriage or termination with gemeprost in the second trimester of pregnancy. Eighteen cases (18.4%) were RPOC