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Autor:
Xiaofei Shao, Qin Zhou, Xin Wang, Jin Deng, Hequn Zou, Haishan Chen, Chongxiang Xiong, Yue Xia
Publikováno v:
Drug Design, Development and Therapy. 14:2221-2233
Purpose Hyperuricemia is an independent risk factor for renal damage and can promote the progression of chronic kidney disease (CKD). In the present study, we employ a rat model to investigate the effects of rosiglitazone (RGTZ), a peroxisome prolife
Publikováno v:
OncoTargets and Therapy. 13:5837-5843
Primary pulmonary diffuse large B cell lymphoma (PPDLBCL) is extremely rare, with fewer than 40 cases reported to date and a lack of systemic analysis. Herein, we present a case of PPDLBCL mimicking metastasis in a heavily treated patient with breast
Autor:
Turan Yaman, Ahmet Uyar, Ismail Celik, Ömer Faruk Keleş, Zabit Yener, Elif Ebru Alkan, Abdulbaki Demir
Publikováno v:
Biotechnic & Histochemistry. 96:28-40
The therapeutic potential and antioxidant capacity of Ferula elaeochytris extract (FE) in the liver, kidney and pancreas of rats with diabetes induced by streptozotocin (STZ) was assessed using biochemistry, histopathology and immunohistochemistry. F
Autor:
Thanat Chaikijurajai, W.H. Wilson Tang
Publikováno v:
Expert Opin Ther Targets
Introduction Coronary artery disease (CAD) poses significant morbidity and mortality globally. Despite significant advances in treatment interventions, residual cardiovascular risks remain unchecked. Recent clinical trials have shed light on the pote
Publikováno v:
OncoTargets and Therapy. 13:4049-4061
Background Cisplatin (DDP) is the first-line chemotherapy agent for the treatment of oral squamous cell carcinoma (OSCC). The emergence of DDP resistance leads to diminished drug efficacy and survival benefit. lncRNA MALAT1 has been considered as one
Autor:
Fatemeh Jahanshahi, Ata Abbasi, Ahmad Reza Dehpour, Mohammad Sheibani, Faiza Mumtaz, Sadaf Nezamoleslami
Publikováno v:
Immunopharmacology and Immunotoxicology. 42:272-279
Background: Ischemia/reperfusion can cause injury to tissues and compromise functionality of organs due to inflammatory processes. Significantly, development of these effects in kidney tissue has b...
Autor:
R. E. Kast
Publikováno v:
Experimental Lung Research
Multiple pharmacological interventions tested over the last decades have failed to reduce ARDS mortality. This short note recounts past data indicating that (i) neutrophils home along an IL-8 gradient, (ii) in ARDS, massive neutrophil accumulation an
Autor:
Iman Fatemi, Mehdi Goudarzi, Saeed Mehrzadi, Mohammad Karimi, Azam Hosseinzadeh, Hamidreza Khalili, Mohammad Javad Khodayar
Publikováno v:
Biotechnic & Histochemistry. 95:532-539
Nephrotoxicity is a significant side effect of doxorubicin (DXN) treatment. We investigated the protective effect of gemfibrozil (GEM) co-administration with DXN on DXN induced nephrotoxicity. We divided 28 male Wistar rats into four groups of seven.
Publikováno v:
OncoTargets and Therapy. 13:3641-3652
Purpose Lung cancer is one of the most prevailing human cancers worldwide. Emerging evidence implies that long non-coding RNA nicotinamide nucleotide transhydrogenase-antisense RNA1 (NNT-AS1) is implicated in the tumorigenesis of lung cancer. Herein,
Autor:
Amy N. Luckenbaugh, Mary E. Hall, Christopher J.D. Wallis, Kelvin A. Moses, Aaron A. Laviana, Zachary Klaassen, Kirk A. Keegan, Heather L. Huelster
Publikováno v:
OncoTargets and Therapy. 13:3571-3581
Introduction The treatment landscape for patients with metastatic hormone-sensitive prostate cancer (mHSPC) has changed dramatically in the past five years, despite little change in the preceding 20 years. Such rapid change can make it difficult for