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Autor:
Jianlin Cui, Yuhao Li, Hao Zhang, Huiling Meng, Yajia Cheng, Peipei Cao, Haiqi Xu, Siwen Zang, Zongjin Li
Publikováno v:
Journal of Inflammation Research. 13:1043-1055
Background The myelin sheath can be damaged by genetic and/or environmental factors, leading to demyelinating diseases, for which effective treatments are lacking. Recently, cyclooxygenase-2 (COX-2) overexpression was detected in demyelinating lesion
Autor:
Thierry Burnouf, David Devos, Yu Wen Wu, Liling Delila, Rifa Widyaningrum, Ming Li Chou, Ouada Nebie
Publikováno v:
Platelets. 32:259-272
Human platelet lysates (HPLs), rich in various growth factors and cell growth-promoting molecules, encompass a new range of blood products that are being used for regenerative medicine, cell therapies, and tissue engineering. Well-characterized dedic
Autor:
Mohammad Obeidat, Marina Ivanovic, Stephanie J.T. Chen, Danniele G. Holanda, Alexandra L Isaacson
Publikováno v:
Ultrastructural Pathology
COVID-19 (from SARS-CoV-2) is the cause of an ongoing pandemic, with an increasing number of cases and significant mortality worldwide. Clinical trials and extensive studies are being conducted on a large scale for a better understanding of the patho
Publikováno v:
OncoTargets and Therapy. 13:11183-11192
Purpose Anaplastic thyroid cancer (ATC) is a kind of rare thyroid cancer with very poor prognosis. Doxorubicin has been approved in ATC treatment as a single agent, but monotherapy still shows no improvement of the total survival in advanced ATC. Len
Autor:
Katsuhiko Nishimori, Shizu Hidema, Kengo Horie, Shohei Kikuchi, Kenju Shimomura, Ryoji Takata, Takaaki Yanai
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 84:2207-2214
Resveratrol (RSV) is a natural polyphenol present in grapes, the skin of peanuts, and several other plants with many health benefits. Autism spectrum disorder (ASD) is a neurodevelopmental disorder that may be linked to neural and synaptic developmen
Publikováno v:
Drug Design, Development and Therapy. 14:5087-5096
Background and purpose Endothelium exerts an important role in releasing vasoactive substances, maintaining the blood flow, regulating the growth of vessels, moderating the process of coagulation, and the balance of fibrinolytic system, the dysfuncti
Publikováno v:
Infection and Drug Resistance. 13:4003-4008
Background The timely and accurate diagnosis of infected nonunion is challenging, and there is a need for more efficient biomarkers. Previous studies have shown that fibrinogen plays an important role in mediating inflammation in bacterial infections
Publikováno v:
OncoTargets and Therapy. 13:11445-11457
Background Gastric cancer is a prevalent primary stomach tumor. Cisplatin is frequently used to treat gastric cancer. However, the resistance of cisplatin in gastric cancer often occurs, which brings a heavy burden to gastric cancer treatment. Method
Publikováno v:
International Journal of Neuroscience. 131:725-734
The aim of this study was to make a volumetric comparison of some medial temporal lobe structures and neuropeptides between the patients of Alzheimer's disease (AD) and healthy individuals.The study comprised of a group of patients diagnosed with mil
Autor:
Terence Chi Chun Tam, James Chung-Man Ho, Ka Yan Chiang, Mary S.M. Ip, David C.L. Lam, Wang Chun Kwok
Publikováno v:
Journal of Chemotherapy. 32:429-436
Maintenance chemotherapy was studied in first line setting for advanced stage non-small cell lung carcinoma (NSCLC). There has not been any data on the role of continuation maintenance chemotherapy in second line setting. A retrospective cohort study