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Publikováno v:
OncoTargets and therapy
Xiaomeng Jiang,1 Menglin Jiang,2 Shuhua Guo,3 Pengpeng Cai,1 Wei Wang,1 Yi Li1 1Department of Digestive, Sir Run Run Hospital, Nanjing Medical University, Nanjing, Jiangsu Province, 211166, People’s Republic of China; 2Biomedical Sciences Departmen
Publikováno v:
Drug Design, Development and Therapy
Wan Nuraini Wan Hasan,1 Kok-Yong Chin,1 Norzana Abd Ghafar,2 Ima Nirwana Soelaiman1 1Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, UKM Medical Centre (UKMMC), Kuala Lumpur 56000, Malaysia; 2Department of Anatomy, Fa
Publikováno v:
Cancer Management and Research. 12:2109-2118
Background It has been demonstrated that circular RNA (circRNA) plays a crucial role in the occurrence and development of tumors, but the diagnostic and predictive value of most circRNAs in tumor patients remains unclear, especially for multiple myel
Autor:
Benjamin Rahmani, Noel L. Smith, Gunjan Joshi, Inefta M Reid, Wayne C. Waltzer, Jason Gandhi, Omar Seyam, Shrey Patel, Sardar Ali Khan
Publikováno v:
International Journal of Neuroscience. 130:464-475
Introduction: The pineal gland, an endocrine organ of the posterior cranial fossa famously involved in sleep and wakefulness, has continually been a topic of scientific advancement and curiosity. Methods: We review present an up-to-date review includ
Autor:
Theano Tatsi, Anna Kalogera-Fountzila, Lemonia Skoura, Vasiliki Tsavdaridou, Eleni Polyzoidou, Dimitrios Parissis, Eleni Grigoriadou, Virginia Giantzi, Panagiotis Ioannidis, Theodoros Karapanayotides, Roza Lagoudaki, Nikolaos Grigoriadis, Ioannis Nikolaidis, Theodora Afrantou, Pamela Melo, Marina Boziki, Sofia Zoidou, Georgios C. Papadopoulos, Evdoxia Gounari, Nikolaos Mandoras, Christos Bakirtzis, Sygkliti-Henrietta Pelidou
Publikováno v:
Neurological Research. 42:209-221
Objectives: Natalizumab (NTZ), a treatment indicated for patients with highly active Relapsing – Remitting Multiple Sclerosis (RRMS), is known to induce increased relative frequency of lymphocytes. Progressive Multifocal Leukoencephalitis (PML) is
Autor:
Donato Santovito, Christian Weber, Ditya Larasati, Melissa Klug, Michael Hristov, Isabell Bernlochner, Karl-Ludwig Laugwitz, Dario Bongiovanni, Moritz von Scheidt
Publikováno v:
Platelets. 32:113-119
Reticulated Platelets (RPs) are large, RNA-rich, prothrombotic and hyperactive platelets known to be elevated in high-risk populations such as diabetics and patients with acute coronary syndrome. High levels of RPs correlate with mortality and advers
Publikováno v:
Biotechnic & Histochemistry. 95:305-316
We investigated the effects of α-lipoic acid (AL) and α-tocopherol (AT) on renal histopathology in a streptozotocin (STZ) induced diabetic rat model. Adult male rats were divided into six groups: group 1, saline only; group 2, AL only; group 3, AT
Autor:
Rui Xue, Youhua Xu, Jianbo Wang, Teng Chen, Ruonan Zhai, Chongting Gao, Ling Xie, Dingkun Gui, Niansong Wang
Publikováno v:
Drug Design, Development and Therapy. 14:527-538
Introduction Epithelial-mesenchymal transition (EMT) may contribute to podocyte dysfunction in diabetic nephropathy (DN). Aiming to identify novel therapeutic options, we investigated the protective effects of Panax notoginseng (PN) on podocyte EMT i
Autor:
Yuka Ohe, Keishi Nakamura, Takahisa Yamaguchi, Jun Kinoshita, Itasu Ninomiya, Koichi Okamoto, Tetsuo Ohta, Hiroto Saito, Sachio Fushida, Hidehiro Tajima
Publikováno v:
Cancer Management and Research. 12:1303-1311
Introduction Platelets are one factor promoting tumor development. Conversely, lymphocytes are one factor for immune protection. The peripheral blood platelets-lymphocyte ratio (PLR) is useful as an inflammation/immune indicator to predict postoperat
Autor:
Yichen Zang, Ronggui Liu, Guijun Zhang, Zhaoyan Ding, Yunping Li, Xiaojuan Zhang, Qinqin Wang
Publikováno v:
Drug Design, Development and Therapy. 14:603-611
Background Chronic kidney disease (CKD) has become a major public health issue. Meanwhile, renal fibrosis caused by diabetic nephropathy can lead to CKD, regardless of the initial injury. It has been previously reported that silibinin or valsartan co