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Autor:
Janakiraman Subramanian, Ossama Tawfik
Publikováno v:
Expert Review of Anticancer Therapy. 21:877-886
Introduction: Non-small cell lung cancer (NSCLC), which accounts for the majority of lung cancer diagnoses in the United States, has many known driver mutations, including MET exon 14 skipping muta...
Autor:
Irini Chatziralli
Publikováno v:
Expert Opinion on Biological Therapy. 21:991-997
Introduction: Diabetic retinopathy (DR) is the most common microvascular complication of diabetes mellitus and the leading cause of blindness in young adults. Prior to anti-vascular endothelial growth factor (anti-VEGF) agents, the treatment of DR wa
Publikováno v:
Biotechnic & Histochemistry. 97:192-198
We investigated the effects of melatonin (Mlt) on hematological characteristics to determine the percentage of alpha-naphthyl acetate esterase (ANAE) positive lymphocytes in rats chronically exposed to cadmium (Cd). We used four groups of male rats:
Autor:
Soo Jin Yun, Eun Mi Choi, Suk Chon, Jin Sun Park, So Young Park, Kwang Sik Suh, Sang Ouk Chin
Publikováno v:
Journal of Environmental Science and Health, Part A. 56:752-761
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is an endocrine disrupting compound and persistent organic pollutant that has been associated with diabetes in several epidemiological studies. Oleuropein, a major phenolic compound in olive fruit, is a supe
Autor:
Xiangming Che, Lin Fan, Guanglin Qiu, Haijiang Wang, Xinhua Liao, Pan-Xing Wang, Jia-Huang Liu
Publikováno v:
Cancer Management and Research
Panxing Wang, Haijiang Wang, Guanglin Qiu, Jiahuang Liu, Lin Fan, Xinhua Liao, Xiangming Che Department of General Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shanxi Province, People’s Republic of ChinaCorrespond
Publikováno v:
OncoTargets and therapy
EGFR-tyrosine kinase inhibitors (TKIs) have revolutionized the treatment for NSCLC. However, acquired drug resistance often occurs after treatment with EGFR-TKIs. EGFR T790M and C797S mutations are the most common resistance mechanism in patients who
Autor:
Ameni Gobena, Hussien Bedru, Aman Jemal, Melaku Fikru, Wardofa Niguse, Awraris Hailu, Sandy Peter, Garoma Getinet
Publikováno v:
Infection and Drug Resistance. 14:1679-1689
Hussien Bedru,1 Melaku Fikru,2 Wardofa Niguse,2 Aman Jemal,2 Garoma Getinet,2 Ameni Gobena,3,4 Awraris Hailu,5 Sandy Peter6 1Department of Public Health, Goba Referral Hospital, Madda Walabu University, Goba, Oromia Region, Ethiopia; 2Tuberculosis Un
Autor:
Salah Al-Waheeb, Khalid Mohammed Khan, Peramaiyan Rajendran, Fatma J. Al-Saeedi, Moudhi Sadan
Publikováno v:
Journal of Receptors and Signal Transduction. 42:261-267
This study aimed to investigate the effect of insulin on the reticuloendothelial system (RES) in the liver and spleen in diabetic rats. Sprague Dawley rats were divided into control, diabetic rats ...
Publikováno v:
Neurological Research. 43:668-676
Objectives: Stroke is an important cause of death and disability. Recent evidence suggests that post-stroke inflammation is an important factor in stroke pathology and a root cause of its lasting c...
Publikováno v:
Expert Review of Anticancer Therapy. 21:693-703
Introduction: The dominant paradigm of sequential therapy of metastatic renal cell carcinoma (mRCC) with single agents has recently been challenged by improved outcomes obtained with combined regimens with immune checkpoint inhibitors. These combined