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Autor:
Po Yen Chen, Wen Chien Ko, Ping-Ing Lee, Po-Ren Hsueh, Chih-Jung Chen, Yhu Chering Huang, Chih Cheng Lai
Publikováno v:
Expert Review of Vaccines. 20:1027-1035
Introduction To combat COVID-19, scientists all over the world have expedited the process of vaccine development. Although interim analyses of clinical trials have demonstrated the efficacy and safety of COVID-19 vaccines, a serious but rare adverse
Autor:
Albaraa Mohammed N. Marran, Sonia Radice, Emilio Clementi, Vera Battini, Robbert P. van Manen, Faizan Mazhar, Marco Pozzi, Michele Gringeri, Giulia Mosini, Carla Carnovale, Shahzad Akram
Publikováno v:
Expert Opinion on Biological Therapy. 21:1281-1290
Background: Studies in patients with immune-mediated inflammatory diseases (IMIDs) have inconsistently suggested that anti-TNFα therapy may be associated with excessive weight gain. Research design and methods: We performed a nested case/non-case an
Autor:
Saad B. Omer, Lauren Pischel, Kavin M. Patel, Mallory K. Ellingson, Azucena Bardají, Laia Vazquez Guillamet
Publikováno v:
Expert Rev Vaccines
INTRODUCTION: Pertussis is a highly contagious respiratory disease that results in disproportionate morbidity and mortality in infants who have yet to receive the primary diphtheria-tetanus-pertussis vaccine series. In the preceding decades numerous
Autor:
Jose Luis Cuadra-Urteaga, Nuria Mulet, Javier Ros, Elena Elez, Iosune Baraibar, Nadia Saoudi Gonzalez, Josep Tabernero, A. Valdivia, Francesc Salvà, D. Marmolejo
Publikováno v:
Expert Opinion on Biological Therapy. 21:1315-1324
Introduction: Colorectal cancer (CRC) is a major public health problem. Despite major progress understanding the biological basis of this tumor added to the incorporation of optimized diagnostic an...
Publikováno v:
Expert Opinion on Biological Therapy. 21:1591-1601
Introduction This review assesses current evidence supporting dose de-escalated rituximab therapy in pemphigus vulgaris, compared to standard lymphoma and rheumatoid arthritis protocols. Primary outcome measures were remission and relapse rates. Adve
Publikováno v:
Drug Design, Development and Therapy
Human epidermal growth factor receptor 2 (HER2) positive cancers account for 15–20% of all breast tumors. Several drugs have been approved in the metastatic setting, including monoclonal antibodies, tyrosine kinase inhibitors (TKI) and, more recent
Publikováno v:
Drug Design, Development and Therapy
Drug repurposing is a feasible strategy in developing novel medications. Regarding the cancer field, scientists are continuously making efforts to redirect conventional drugs into cancer treatment. This approach aims at exploring new applications in
Publikováno v:
Drug Design, Development and Therapy
Guohu Weng,1 Bo Zhou,2 Tao Liu,3 Zhengxin Huang,2 Shixiong Huang3 1Department of Encephalopathy, Hainan Provincial Hospital of Traditional Chinese Medicine, Haikou, 570203, Hainan, People’s Republic of China; 2Department of Cardiology, Hainan Provi
Publikováno v:
Drug Design, Development and Therapy
Neovascular age-related macular degeneration (nAMD) treatment has been revolutionized by the introduction of vascular endothelial growth factor antagonists (anti-VEGF), but the need for frequent intravitreal injections poses a heavy burden to patient
Publikováno v:
Drug Design, Development and Therapy
Yueyue Liu, Qian Zhang, Chao Lu, Wei Hu Department of Clinical Pharmacology, The Second Hospital of Anhui Medical University, Hefei, 230601, People’s Republic of ChinaCorrespondence: Chao Lu; Wei HuDepartment of Clinical Pharmacology, The Second Ho