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Autor:
Po Yen Chen, Wen Chien Ko, Ping-Ing Lee, Po-Ren Hsueh, Chih-Jung Chen, Yhu Chering Huang, Chih Cheng Lai
Publikováno v:
Expert Review of Vaccines. 20:1027-1035
Introduction To combat COVID-19, scientists all over the world have expedited the process of vaccine development. Although interim analyses of clinical trials have demonstrated the efficacy and safety of COVID-19 vaccines, a serious but rare adverse
Autor:
Saad B. Omer, Lauren Pischel, Kavin M. Patel, Mallory K. Ellingson, Azucena Bardají, Laia Vazquez Guillamet
Publikováno v:
Expert Rev Vaccines
INTRODUCTION: Pertussis is a highly contagious respiratory disease that results in disproportionate morbidity and mortality in infants who have yet to receive the primary diphtheria-tetanus-pertussis vaccine series. In the preceding decades numerous
Autor:
Burcu Temizoz, Ken Ishii
Publikováno v:
Expert Review of Vaccines. 20:527-544
Introduction: Innate immunity is armed with interferons (IFNs) that link innate immunity to adaptive immunity to generate long-term and protective immune responses against invading pathogens and tumors. However, regulation of IFN production is crucia
Autor:
Luwy Musey, Ulrike K. Buchwald, Kelly D Johnson, Allan W. Cripps, Michael S. Niederman, Temitope Folaranmi
Publikováno v:
Expert Review of Vaccines. 20:257-267
Introduction: Immunogenicity studies evaluating sequential administration of pneumococcal conjugate vaccine (PCV) followed by 23-valent pneumococcal polysaccharide vaccine (PPSV23) or revaccination with PPSV23 have raised concerns that PPSV23 may not
Publikováno v:
Expert Review of Vaccines. 19:1105-1114
There are currently no effective treatments for Methamphetamine (METH) addiction and psychotherapy remains the sole treatment option. The development of immunopharmacotherapies for the treatment of drug addiction, overdose, and relapse management app
Publikováno v:
Expert Opin Ther Targets
INTRODUCTION: Antipsychotic drugs that target the dopamine system have been central to the treatment of schizophrenia, but their limitations in efficacy, tolerability, and precision necessitate improved treatment strategies. Multiple lines of researc
Autor:
Hongmei Wang, Wei Shi, Yonghong Yang, Jikui Deng, Kun-Ling Shen, Qiang Chen, Jingmin Wang, Jiaosheng Zhang, Kaihu Yao, Kai Zhou, Wenkui Dai, Gan Xie, Jinyan Ye, Heping Wang, Yuejie Zheng, Dan-Xia Wu, Dongfang Li, Xiang Ma
Publikováno v:
Expert Review of Vaccines. 19:1093-1099
The resurgence of Bordetella pertussis infections leading to whooping cough is a concern in many parts of the world. The number of pertussis cases in China has increased significantly since 2013. I...
Publikováno v:
Expert Opin Ther Targets
INTRODUCTION: Inflammasomes are central to atherosclerotic vascular dysfunction with regulatory effects on inflammation, immune modulation, and lipid metabolism. The NLRP3 inflammasome is a critical catalyst for atherogenesis thus highlighting its im
Autor:
Thanat Chaikijurajai, W.H. Wilson Tang
Publikováno v:
Expert Opin Ther Targets
Introduction Coronary artery disease (CAD) poses significant morbidity and mortality globally. Despite significant advances in treatment interventions, residual cardiovascular risks remain unchecked. Recent clinical trials have shed light on the pote
Autor:
Lamine Soumahoro, Nicolas Lecrenier, Bruce A. Mungall, Jan Olbrecht, Javier Nieto Guevara, Alen Marijam
Publikováno v:
Expert Review of Vaccines. 19:247-265
Introduction: Pneumococcal diseases (including pneumonia, meningitis and sepsis) are among the leading vaccine-preventable causes of death in under-5-year-olds. Pneumococci are also one of the main bacterial pathogens associated with acute otitis med