Zobrazeno 1 - 10
of 121
pro vyhledávání: ''
Autor:
Xin Liu, Motao Zhu, Lang Chen, Changsheng Xing, Chen Qian, Chaoran Li, Helen Yicheng Wang, Chuntang Fu, Guangtong Deng, Rongfu Wang
Publikováno v:
Autophagy
Macroautophagy/autophagy-related proteins regulate infectious and inflammatory diseases in autophagy-dependent or -independent manner. However, the role of a newly identified mammalian-specific autophagy protein-BECN2 (beclin 2) in innate immune regu
Publikováno v:
Cell Cycle
The long non-coding RNA HLA complex P5 (HCP5) is extensively related to cancer chemoresistance, while its function in gastric cancer (GC) has not been well elucidated yet. Here, the role and mechanism of HCP5 in regulating the chemoresistance of GC t
Autor:
Tong-Cun Zhang, Chang Wang, Qing-Qing Dong, Rui Huang, Zhongyuan Li, Nan Wang, Wei Zhao, Yajian Song, Hai-Jie Hu, Xue-Gang Luo
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 85:1395-1404
Liraglutide is an analogue of human glucagon-like peptide-1 (GLP-1), an endogenous intestinal hormone which play essential roles in the regulation of glycolipid metabolism. To investigate the role of lactic acid bacteria (LAB) in the lipid-lowering e
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 85:643-655
The long-term imposition of pressure overload on the cardiac tissue causes left ventricular hypertrophy (LVH) and cardiac fibrosis. Pinitol has been reported to possess antioxidant potential. The aim was to evaluate the efficacy of pinitol against pr
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 85:579-586
PGC-1α expression increases in skeletal muscles during exercise and regulates the transcription of many target genes. In this study, we conducted a metabolomic analysis on the blood of transgenic mice overexpressing PGC-1α in its skeletal muscle (P
Publikováno v:
Cell Cycle
This project aimed to investigate the protective mechanism of sufentanil pretreatment on myocardial ischemia-reperfusion injury (IRI). An in vivo rat model of myocardial IRI and an in vitro cultured cardiomyocyte model of hypoxia-reoxygenation (H/R)
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 85:520-527
The purpose of this study is to investigate the protective effect of gambogenic acid (GA) in acetaminophen (APAP)-induced hepatotoxicity in rat models. GA (10 mg/kg) was administered intraperitoneal (i.p.) to rats for 7 consecutive days followed by A
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 85:378-385
Apoptosis and inflammation were the main hallmarks of sepsis-induced cardiomyopathy (SIC). Yes-associated protein isoform 1 (Yap1) and miR-484 were involved in mitochondrial fission and apoptosis, especially proapoptotic roles in SIC. Here, we invest
Autor:
Ying Jin, Zhifei Xu, Jinjin Shao, Peihua Luo, Qiaojun He, Nengming Lin, Ying Zhang, Bo Yang, Hao Yan, Jiangxia Du, Xueqin Chen
Publikováno v:
Autophagy
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Liver dysfunction is an outstanding dose-limiting toxicity of gefitinib, an EGFR (epidermal growth factor receptor)-tyrosine kinase inhibitor (TKI), in the treatment of EGFR mutation-positive non-small cell lung cancer (NSCLC). We aimed to elucidate
Autor:
Katsuhiko Nishimori, Shizu Hidema, Kengo Horie, Shohei Kikuchi, Kenju Shimomura, Ryoji Takata, Takaaki Yanai
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 84:2207-2214
Resveratrol (RSV) is a natural polyphenol present in grapes, the skin of peanuts, and several other plants with many health benefits. Autism spectrum disorder (ASD) is a neurodevelopmental disorder that may be linked to neural and synaptic developmen