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Autor:
Canan Yildirim, Yesim Coskun
Publikováno v:
International Journal of Neuroscience. 133:322-326
Despite the development of new antiseizure drugs (ASDs), around one third of epilepsy patients become refractory to treatment or experience adverse events due to ASDs. Therefore, discovery of new ASDs and new therapy options are crucial to improve th
Publikováno v:
Journal of Dermatological Treatment. 33:2051-2056
In reaction to skin injury in genetically predisposed persons, the keloid is formed and marked by benignant overgrowth of dermic collagen. Intralesional triamcinolone was used in the treatment of keloids with varying results.Intralesional triamcinolo
Autor:
Paolo Persichetti, Morariu Sh, Giovanni Pellacani, Iris Zalaudek, Claudio Conforti, Francesco Segreto, Giovanni Francesco Marangi, Domenico Piccolo, Caterina Dianzani, Nicoleta Neagu, Marina Agozzino
Publikováno v:
Journal of Dermatological Treatment. 33:1816-1837
Melasma is a common chronic refractory disorder of pigmentation affecting people with darker skin types. Overall prevalence varies between 8.8% and 40%, depending on the ethnicity of the population and the geographical area. Therapeutic management of
Publikováno v:
Xenobiotica. 51:1292-1302
Zolmitriptan (ZOL), a member of triptans, has been used for the treatment of migraine with definite therapeutic effects. However, several cases of liver injury associated with ZOL have been reported and the underlying mechanisms remain unclear.The pr
Publikováno v:
Expert Opinion on Investigational Drugs. 30:1125-1140
Introduction Due to new insights into the pathogenesis of inflammatory myopathies -in short myositis- and the urgent need for new treatment options in patients who are refractory to standard therapy, multiple novel drugs have been developed and studi
Publikováno v:
Expert Review of Anti-infective Therapy. 20:621-629
Background Treatment and control of schistosomiasis rely on a single drug, praziquantel. New orally active antischistosomals featuring novel molecular scaffolds are urgently needed to prevent the emergence of resistance. Methods We screened 400 drug-
Autor:
Gordana Zavišić, Sanja Vranješ-Đurić, Dalibor M. Stanković, Željko Prijović, Marko Perić, Marija Mirković, Drina Janković, Magdalena Radović, Zorana Milanović
Publikováno v:
International Journal of Radiation Biology
PURPOSE Recent studies with doxycycline as adjuvant therapy to conventional chemotherapy have shown promising results in cancer therapy. The current study aimed to examine the capability of 177Lu-labeled tetracycline ligand, doxycycline hyclate, to u
Autor:
Shi-Yi Xu, Qi Wang, Ruo-Yi Hao, Xue-Ying Li, Jie Li, Xue-Ying Yan, Hui Su, Xi Chen, Xing-Yu Zhu
Publikováno v:
Journal of Liposome Research. 32:107-118
The selectivity of chemotherapeutic agents for liver cancer is poor. When they kill tumour cells, they produce serious adverse reactions in the whole body and multidrug resistance (MDR) is also a major hurdle in liver cancer chemotherapy. Combination
Publikováno v:
Journal of Dermatological Treatment. 33:1838-1843
Atopic dermatitis (AD) is a common chronic inflammatory condition. Ustekinumab is a human monoclonal antibody approved for psoriasis, that targets the interleukin (IL)-12 and IL-23, and it may also play a role in AD. Administration of ustekinumab in
Autor:
Chii-Shan Lin, Yee-Jen Wu, Chih-Fen Huang, Shin-Yi Lin, Hao-Cheng Kang, Fe-Lin Lin Wu, Yi-Wen Chen, Chia-Wei Wu, Pin-Zi Chen, Li-Jiuan Shen, Yen-Ming Huang
Publikováno v:
Postgraduate Medicine. 133:964-973
Objective: The study aimed to evaluate the improvement of patient knowledge of warfarin use, satisfaction with pharmacists, and the quality of international normalized ratio (INR) control after the implementation of an anticoagulant clinic (ACC) serv