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Autor:
Ricardo P Garay
Publikováno v:
Expert Opinion on Investigational Drugs. 30:749-758
Introduction:Several pharmacological drugs have shown proof of concept for longevity in animal models. I aimed to identify and review those longevity drug candidates that are undergoing clinical tr...
Publikováno v:
Expert Review of Cardiovascular Therapy. 19:575-580
Introduction: Statins are powerful lipid-lowering agents which reduce cardiovascular (CV)–related morbidity and mortality. However, a large proportion of patients cannot attain the target low-densi...
Autor:
Sepehr Feizi, Ahmad Kheirkhah, Alireza Baradaran Rafii, Mohammad-Hasan Alemzadeh-Ansari, Hamed Esfandiari
Publikováno v:
Ocular Immunology and Inflammation. 30:1701-1706
To investigate the safety and efficacy of topical erythropoietin for the treatment of scleral necrosis.This study enrolled eight consecutive patients with scleral necrosis due to previous ocular surgery, rheumatoid arthritis-associated necrotizing an
Publikováno v:
Chronobiology International. 38:1673-1691
Effects of photoperiodicity caused by both the age and individual physiological reactivity estimated by resistance to hypobaric hypoxia on the levels of lipid peroxidation, protein oxidation (aldehydic and ketonic derivatives), total antioxidant capa
Autor:
Pedro Balikian, Victor José Bastos-Silva, Alisson H Marinho, Sara Learsi, José Bruno Bezerra da Silva, Filipe Antônio de Barros Sousa, Gustavo Gomes de Araujo
Publikováno v:
European Journal of Sport Science. 22:1065-1072
The present study tested the hypothesis that acute metformin would increase peak power measured during a Wingate test. Fourteen men (24 ± 6 years; 75.8 ± 10.2 kg; 177 ± 7 cm) participated in four test sessions, conducted in a crossover, counterbal
Autor:
Marieke E. Gimbel, J M Ten Berg
Publikováno v:
Expert Opinion on Drug Safety. 20:1545-1552
Introduction: Dual antiplatelet therapy (DAPT) is standard treatment for patients with acute coronary syndrome (ACS). This includes lifelong aspirin combined with a P2Y(12) inhibitor for 1 year. The indication for one of the P2Y(12) inhibitors (clopi
Autor:
Peter Magnusson, Charles Wollmuth, Giustino Varrassi, Frank Breve, Jo Ann LeQuang, Joseph V. Pergolizzi, Robert W. Taylor
Publikováno v:
Expert Opinion on Pharmacotherapy. 22:1119-1126
Opioid analgesia for acute painful conditions has come under increasing scrutiny with the public health crisis of opioid overdose, leading clinicians to seek nonopioid alternatives, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminop
Autor:
Michael Andersson, Niklas Rye Jørgensen, Peter Schwarz, Kristian Buch-Larsen, Lars Thorbjørn Jensen
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 81:425-431
Adjuvant treatment for post-menopausal women with early breast cancer (BC) includes aromatase inhibitors (AI), known to decrease bone mineral density (BMD). In this study, we investigate whether denosumab is a valid second option for patients unable
Autor:
Jose Luis Cuadra-Urteaga, Nuria Mulet, Javier Ros, Elena Elez, Iosune Baraibar, Nadia Saoudi Gonzalez, Josep Tabernero, A. Valdivia, Francesc Salvà, D. Marmolejo
Publikováno v:
Expert Opinion on Biological Therapy. 21:1315-1324
Introduction: Colorectal cancer (CRC) is a major public health problem. Despite major progress understanding the biological basis of this tumor added to the incorporation of optimized diagnostic an...
Autor:
Alessandro Torre, Marta Oldani, Federico Zicarelli, Salvatore Parrulli, Alessandro Invernizzi
Publikováno v:
Ocular Immunology and Inflammation. 30:1595-1598
Purpose: To report a case of iris ischemia in an eye affected by Cytomegalovirus (CMV)-related Chronic Retinal Necrosis (CRN) with partial reperfusion after antiviral therapy demonstrated by optical coherence tomography angiography (OCTA).Methods: Re