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Publikováno v:
Expert Opinion on Investigational Drugs. 30:1125-1140
Introduction Due to new insights into the pathogenesis of inflammatory myopathies -in short myositis- and the urgent need for new treatment options in patients who are refractory to standard therapy, multiple novel drugs have been developed and studi
Autor:
Francine M. Foss, Suzanne Xu
Publikováno v:
Expert Review of Anticancer Therapy. 21:1017-1028
The most common types of CTCL are mycosis fungoides (MF) and Sézary syndrome (SS). In both MF and SS, complete responses to treatment are uncommon. Recent developments and understanding of the biology of MF/SS have led to novel agents which may offe
Publikováno v:
Expert Opinion on Pharmacotherapy. 22:2105-2111
Introduction: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce blood glucose and glycosylated haemoglobin (HbA1c), the risk of hospitalization for heart failure (HF) and the incidence of serious adverse kidney function events (chronic kidney
Publikováno v:
Expert Review of Neurotherapeutics. 21:755-778
Introduction: Nabiximols, a cannabinoid-based oromucosal spray, is indicated as add-on therapy for symptomatic relief of spasticity in persons with multiple sclerosis (MS). This review compiles tol...
Publikováno v:
Expert Review of Pharmacoeconomics & Outcomes Research. 22:37-44
Background: Chronic heart failure (CHF) is a clinical status and a progressive health disorder extremely related to increased morbidity and mortality worldwide. Accordingly, this study aimed to assess systematic review of literature on cost-effective
Autor:
Jan van Amsterdam, Wim van den Brink
Publikováno v:
Expert Opinion on Drug Safety. 21:83-94
Backgrounds: Ketamine is a dissociative anesthetic that is currently considered for several new indications. Aim: To deduce the safety of long-term ketamine treatment using the harm of heavy recreational (non-medical) ketamine use as a proxy for maxi
Publikováno v:
Expert Opinion on Pharmacotherapy. 22:2199-2220
Given the relationship between the pathogenesis of obesity and type 2 diabetes mellitus (T2DM) as well as their significant health consequences, treatment strategies that can induce weight loss while achieving glycemic control are needed. Novel weigh
Publikováno v:
Expert Review of Clinical Pharmacology. 14:1267-1278
Introduction Acetylcysteine is the standard treatment for preventing hepatotoxicity caused by acetaminophen overdose. Several novel approaches to the management of acetaminophen overdose have been suggested to improve patient safety by reducing adver
Autor:
Zhe Huang, Caijin Zhou, Rihong Chen, Linxia Chen, Weiwei Wang, Feipeng Xu, Qingwen Xu, Renwei Huang
Publikováno v:
Journal of Chemotherapy. 34:35-44
Along with the occurrence of cisplatin resistance, treatment on gastric cancer (GC) becomes difficult. Therefore, researches on new therapeutic methods to revert cisplatin resistance are becoming increasingly urgent. qRT-PCR was used to quantify the
Autor:
Åke SjöholmÅke Sjöholm
Publikováno v:
Expert Opinion on Pharmacotherapy. 22:2143-2148
Introduction: Insulin and its analogues have so far been the only approved treatment for type 1 diabetes in Europe, while in the US, the amylin analog pramlintide is approved for adjuvant use with ...