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Publikováno v:
Expert Opinion on Investigational Drugs. 30:1125-1140
Introduction Due to new insights into the pathogenesis of inflammatory myopathies -in short myositis- and the urgent need for new treatment options in patients who are refractory to standard therapy, multiple novel drugs have been developed and studi
Publikováno v:
Expert Opinion on Pharmacotherapy. 22:2105-2111
Introduction: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce blood glucose and glycosylated haemoglobin (HbA1c), the risk of hospitalization for heart failure (HF) and the incidence of serious adverse kidney function events (chronic kidney
Publikováno v:
Expert Opinion on Pharmacotherapy. 22:2199-2220
Given the relationship between the pathogenesis of obesity and type 2 diabetes mellitus (T2DM) as well as their significant health consequences, treatment strategies that can induce weight loss while achieving glycemic control are needed. Novel weigh
Autor:
Zhe Huang, Caijin Zhou, Rihong Chen, Linxia Chen, Weiwei Wang, Feipeng Xu, Qingwen Xu, Renwei Huang
Publikováno v:
Journal of Chemotherapy. 34:35-44
Along with the occurrence of cisplatin resistance, treatment on gastric cancer (GC) becomes difficult. Therefore, researches on new therapeutic methods to revert cisplatin resistance are becoming increasingly urgent. qRT-PCR was used to quantify the
Autor:
Åke SjöholmÅke Sjöholm
Publikováno v:
Expert Opinion on Pharmacotherapy. 22:2143-2148
Introduction: Insulin and its analogues have so far been the only approved treatment for type 1 diabetes in Europe, while in the US, the amylin analog pramlintide is approved for adjuvant use with ...
Autor:
Ricardo P Garay
Publikováno v:
Expert Opinion on Investigational Drugs. 30:749-758
Introduction:Several pharmacological drugs have shown proof of concept for longevity in animal models. I aimed to identify and review those longevity drug candidates that are undergoing clinical tr...
Autor:
Peter Magnusson, Charles Wollmuth, Giustino Varrassi, Frank Breve, Jo Ann LeQuang, Joseph V. Pergolizzi, Robert W. Taylor
Publikováno v:
Expert Opinion on Pharmacotherapy. 22:1119-1126
Opioid analgesia for acute painful conditions has come under increasing scrutiny with the public health crisis of opioid overdose, leading clinicians to seek nonopioid alternatives, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminop
Publikováno v:
Expert Opinion on Pharmacotherapy. 22:2087-2094
IntroductionSodium-glucose cotransporter-2 inhibitors (SGLT2is) are proven to ameliorate kidney and heart failure in patients with type 2 diabetes (T2D), in addition to improving glycemic controls. Canagliflozin is a SGLT2i and has proved beneficial
Publikováno v:
Journal of Chemotherapy. 33:547-553
The objective of this study was to evaluate the efficacy of various dosing regimens of vancomycin, teicoplanin, linezolid and daptomycin against methicillin-resistant Staphylococcus aureus (MRSA) in neutropenic patients with cancer. Monte Carlo simul
Autor:
Huaiyu Jia, Liqiong Chen, Na Huang, Tieli Zhou, Kaihang Yu, Jianming Cao, Yishuai Lin, Lijiang Chen, Xiangkuo Zheng, Wenli Liao
Publikováno v:
Infection and Drug Resistance
Liqiong Chen,1 Kaihang Yu,2 Lijiang Chen,1 Xiangkuo Zheng,1 Na Huang,1 Yishuai Lin,2 Huaiyu Jia,1 Wenli Liao,1 Jianming Cao,2 Tieli Zhou1 1Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejia