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Publikováno v:
Journal of Dermatological Treatment. 33:1838-1843
Atopic dermatitis (AD) is a common chronic inflammatory condition. Ustekinumab is a human monoclonal antibody approved for psoriasis, that targets the interleukin (IL)-12 and IL-23, and it may also play a role in AD. Administration of ustekinumab in
Autor:
Chii-Shan Lin, Yee-Jen Wu, Chih-Fen Huang, Shin-Yi Lin, Hao-Cheng Kang, Fe-Lin Lin Wu, Yi-Wen Chen, Chia-Wei Wu, Pin-Zi Chen, Li-Jiuan Shen, Yen-Ming Huang
Publikováno v:
Postgraduate Medicine. 133:964-973
Objective: The study aimed to evaluate the improvement of patient knowledge of warfarin use, satisfaction with pharmacists, and the quality of international normalized ratio (INR) control after the implementation of an anticoagulant clinic (ACC) serv
Autor:
Matthew E. Falagas, Margarita Kyriakidou, Anastasios Kapaskelis, Katerina G Tsegka, Georgios L Voulgaris
Publikováno v:
Expert Review of Anti-infective Therapy. 20:33-43
Fosfomycin is a wide spectrum bactericidal antibiotic with a unique mode of action, low toxicity, and good penetration in tissues with deep-seated infections, including bone and joint infections.Data were extracted from 19 published articles. Three h
Autor:
Jan van Amsterdam, Wim van den Brink
Publikováno v:
Expert Opinion on Drug Safety. 21:83-94
Backgrounds: Ketamine is a dissociative anesthetic that is currently considered for several new indications. Aim: To deduce the safety of long-term ketamine treatment using the harm of heavy recreational (non-medical) ketamine use as a proxy for maxi
Autor:
Maria do Socorro de Brito Lopes, Francielle Alline Martins, José Luiz Silva Sá, Thais Teixeira da Silva, Pedro Marcos de Almeida, Júlia Braga Martins
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 84:769-782
Kavain, kavalactone, present in Piper methysticum exhibits anticonvulsive, analgesic, anxiolytic, antiepileptic, antithrombotic, anti-inflammatory and antioxidant properties. Given its importance, ...
Autor:
Steven R. Goldstein
Publikováno v:
Climacteric. 25:56-59
Selective estrogen receptor modulators (SERMs) are synthetic molecules that bind to the estrogen receptor and can have agonistic activity in some tissues while being estrogen antagonistic in others. While not all SERMs are clinically available in all
Autor:
Mehmet Bülbül, Bilge Aydın Türk, Mehmet Can Nacar, Muhittin Onderci, Cihat Ucar, Talip Karaçor, Ali Parlar
Publikováno v:
Biotechnic & Histochemistry. 97:254-260
Carbamazepine (CMZ) increases estrogen metabolism by inducing cytochrome P450 (CYP3A4). We investigated whether CMZ is protective against endometrial hyperplasia (EH). We used 32 female Wistar albino rats divided into four equal groups: the control g
Publikováno v:
Acta clinica Belgica
Introduction: Splenic abscesses are a rare medical entity with high mortality, with Clostridium perfringens being an exceptional pathogen. We present the first case describing an abscess of the spleen in a patient undergoing treatment with adalimumab
Publikováno v:
Acta Oncologica. 60:1100-1105
Background With the first- and second-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), clinical benefit and rash correlate together. EGFR TKI-induced rash can be alleviated with topical corticosteroids and tetracy
Publikováno v:
Journal of Dermatological Treatment. 33:2068-2074
Background The topical corticosteroid halobetasol propionate (HP) and retinoid tazarotene (TAZ) are effective in psoriasis treatment. Fixed-combination HP 0.01%/TAZ 0.045% lotion has demonstrated efficacy and safety in moderate-to-severe plaque psori